Pular para o conteúdo
Merck
Todas as fotos(2)

Key Documents

View All Documentation

Z103

Sigma-Aldrich

Zolpidem

≥98% (HPLC), solid, benzodiazepine receptor agonist

Sinônimo(s):

N,N,6-Trimethyl-2-(4-methylphenyl)-imidazo[1,2-a]pyridine-3-acetamide

Faça loginpara ver os preços organizacionais e de contrato
Todas as fotos(2)

About This Item

Fórmula empírica (Notação de Hill):
C19H21N3O
Número CAS:
82626-48-0
Peso molecular:
307.39
Número MDL:
MFCD00153885
Código UNSPSC:
12352200
ID de substância PubChem:
24902172
NACRES:
NA.77

product name

Zolpidem, ≥98% (HPLC), solid

Nível de qualidade

100

Ensaio

≥98% (HPLC)

forma

solid

controle de medicamentos

USDEA Schedule IV; Home Office Schedule 4.1; psychotrope (France); kontrollierte Droge in Deutschland; regulated under CDSA - not available from Sigma-Aldrich Canada; psicótropo (Spain); Decreto Lei 15/93: Tabela IV (Portugal)

cor

white

solubilidade

45% (w/v) aq 2-hydroxypropyl-β-cyclodextrin: 0.3 mg/mL
DMSO: >10 mg/mL
ethanol: 50 mg/mL
methanol: 50 mg/mL
H2O: insoluble
dilute aqueous base: insoluble

originador

Sanofi Aventis

cadeia de caracteres SMILES

CC1=CN2C(C=C1)=NC(C3=CC=C(C)C=C3)=C2CC(N(C)C)=O

InChI

1S/C19H21N3O/c1-13-5-8-15(9-6-13)19-16(11-18(23)21(3)4)22-12-14(2)7-10-17(22)20-19/h5-10,12H,11H2,1-4H3

chave InChI

ZAFYATHCZYHLPB-UHFFFAOYSA-N

Informações sobre genes

human ... GABRA1(2554) , GABRA2(2555) , GABRA3(2556) , GABRA5(2558) , GABRA6(2559) , GABRB1(2560) , GABRG2(2566)
rat ... Gabra1(29705) , Gabra2(29706) , Gabra5(29707) , Tspo(24230)

Procurando produtos similares? Visita Guia de comparação de produtos

Ações bioquímicas/fisiológicas

Potent and selective agonist for the benzodiazepine receptor associated with the GABAA receptor; hypnotic.

Características e benefícios

This compound is a featured product for Neuroscience research. Click here to discover more featured Neuroscience products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.
This compound is featured on the GABAA Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
This compound was developed by Sanofi Aventis. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Pictogramas

Exclamation markEnvironment
GHS07,GHS09

Palavra indicadora

Warning

Frases de perigo

H302,H336,H411

Classificações de perigo

Acute Tox. 4 Oral - Aquatic Chronic 2 - STOT SE 3

Órgãos-alvo

Central nervous system

Código de classe de armazenamento

11 - Combustible Solids

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

Equipamento de proteção individual

Eyeshields, Gloves, type N95 (US)

Certificados de análise (COA)

Busque Certificados de análise (COA) digitando o Número do Lote do produto. Os números de lote e remessa podem ser encontrados no rótulo de um produto após a palavra “Lot” ou “Batch”.

Já possui este produto?

Encontre a documentação dos produtos que você adquiriu recentemente na biblioteca de documentos.

Visite a Biblioteca de Documentos

Ji-Yeong Byeon et al.
Archives of pharmacal research, 41(8), 861-866 (2018-08-18)
Zolpidem is indicated for the short-term treatment of insomnia and it is predominantly metabolized by CYP3A4, and to a lesser extent by CYP2C19, CYP1A2, and CYP2C9. Therefore, we evaluated the effects of CYP2C19 genetic polymorphisms on the pharmacokinetics of zolpidem
Sara C Mednick et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 33(10), 4494-4504 (2013-03-08)
An important function of sleep is the consolidation of memories, and features of sleep, such as rapid eye movement (REM) or sleep spindles, have been shown to correlate with improvements in discrete memory domains. Because of the methodological difficulties in
Hsin-I Shih et al.
Medicine, 94(17), e809-e809 (2015-05-02)
We evaluate the effects of zolpidem use to develop dementia or Alzheimer disease from the Taiwan National Health Insurance Research Database (NHIRD).A retrospective population-based nested case-control study. Newly diagnosed dementia patients 65 years and older and controls were sampled. A
Eunmi Kim et al.
Forensic science international, 269, 50-55 (2016-11-21)
The southern area of South Korea consists of three parts; Busan, Ulsan and Gyeongsangnam-do. Busan Institute of National Forensic Service (NFS) performed about 50,000 cases throughout the southern area in 2014, occupying over 15% of total cases covered by NFS.
Franck Da-Silva et al.
Journal of pharmaceutical sciences, 107(7), 1957-1972 (2018-03-11)
The objective was to compare, with the same data set, the predictive performance of 3 in vitro assays of hepatic clearance (CL), namely, micropatterned cocultures (also referring to HepatoPac®) and suspension as well as monolayer hepatocytes to define which assay is
Exibir todos os documentos relacionados

Nossa equipe de cientistas tem experiência em todas as áreas de pesquisa, incluindo Life Sciences, ciência de materiais, síntese química, cromatografia, química analítica e muitas outras.

Entre em contato com a assistência técnica