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Z-003

Supelco

Zopiclone solution

1.0 mg/mL in acetonitrile, ampule of 1 mL, certified reference material, Cerilliant®

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About This Item

Fórmula empírica (Notação de Hill):
C17H17ClN6O3
Número CAS:
43200-80-2
Peso molecular:
388.81
Número CE:
200-835-2
Código UNSPSC:
41116107
NACRES:
NA.24

grau

certified reference material

forma

liquid

Características

Snap-N-Spike®/Snap-N-Shoot®

embalagem

ampule of 1 mL

fabricante/nome comercial

Cerilliant®

concentração

1.0 mg/mL in acetonitrile

técnica(s)

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

aplicação(ões)

clinical testing

formato

single component solution

temperatura de armazenamento

−20°C

cadeia de caracteres SMILES

C[NH+]1CCN(CC1)C(=O)OC2N(C(=O)c3nccnc23)c4ccc(Cl)cn4

InChI

1S/C17H17ClN6O3/c1-22-6-8-23(9-7-22)17(26)27-16-14-13(19-4-5-20-14)15(25)24(16)12-3-2-11(18)10-21-12/h2-5,10,16H,6-9H2,1H3/p+1

chave InChI

GBBSUAFBMRNDJC-UHFFFAOYSA-O

Categorias relacionadas

Descrição geral

A certified solution standard suitable for use in LC/MS or GC/MS applications for clinical toxicology, forensic analysis, pharmaceutical research, or urine drug testing.  Zopiclone is a non-benzodiazepine hypnotic sold under the trade names Imovane® and ZImovane® and is prescribed for the treatment of insomnia.

Aplicação

  • Zopiclone solution pharmacological research applications: Utilized in developing and validating analytical methods for detecting z-drugs in biological samples, enhancing forensic toxicology and clinical diagnostics (Chauhan et al., 2024).
  • Zopiclone as a GABA receptor modulator in biochemistry: Investigated for its role in drug-facilitated crimes, particularly its identification through presumptive spot tests, which is crucial for forensic analysis (Chauhan and Sharma, 2023).
  • Zopiclone solution for sleep disorder experimental studies: Analyzed for its effects on hyperlipidemic conditions in postmortem blood, contributing to forensic science and medical research (Elenstål et al., 2023).
  • Zopiclone liquid formulation stability in laboratory conditions: Reviewed for long-term medication use in insomnia treatments, providing essential data on clinical safety and efficacy (Zee et al., 2023).
  • Zopiclone in vitro receptor binding assays methodology: Employed in evaluating the toxicity of zopiclone impurities, supporting the development of safer pharmaceutical products (Yin et al., 2023).

Informações legais

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Imovane is a registered trademark of Sanofi-Aventis
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

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Pictogramas

FlameExclamation mark
GHS02,GHS07

Palavra indicadora

Danger

Classificações de perigo

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Flam. Liq. 2

Código de classe de armazenamento

3 - Flammable liquids

Classe de risco de água (WGK)

WGK 2

Ponto de fulgor (°F)

35.6 °F - closed cup

Ponto de fulgor (°C)

2 °C - closed cup

Certificados de análise (COA)

Busque Certificados de análise (COA) digitando o Número do Lote do produto. Os números de lote e remessa podem ser encontrados no rótulo de um produto após a palavra “Lot” ou “Batch”.

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Judith Peacey et al.
The Journal of nervous and mental disease, 200(1), 83-87 (2012-01-03)
Adult patients (N = 100) being treated for acute psychiatric illness were interviewed about their sleep problems and attitudes toward available treatments. Most (74%) were using at least one prescribed psychotropic drug with hypnotic or sedative effects. Participants prescribed three
[Determination of zopiclone in serum by gas chromatographic method].
Zi-ru Cheng et al.
Zhonghua lao dong wei sheng zhi ye bing za zhi = Zhonghua laodong weisheng zhiyebing zazhi = Chinese journal of industrial hygiene and occupational diseases, 30(4), 314-315 (2012-07-19)
To breathe, perchance not to wake?
David M Rapoport
Journal of applied physiology (Bethesda, Md. : 1985), 112(2), 247-248 (2011-10-29)
Milena Araújo Tonon et al.
Analytical and bioanalytical chemistry, 405(1), 267-273 (2012-11-07)
A new high-performance liquid chromatographic method with triple quadrupole mass spectrometry detection was developed and validated for the quantification of zopiclone enantiomers in rat brain samples. Zopiclone enantiomers were resolved on a CHIRALPAK AD column with a mobile phase consisting
Nico J Diederich et al.
Journal of the neurological sciences, 314(1-2), 12-19 (2011-11-29)
Sleep symptoms in Parkinson's disease (PD) are frequent and have multifactorial and multilayered causes. Primary involvement of sleep/wake regulating centers in the brainstem, sleep problems caused by the nocturnal manifestation of motor and dysautonomic signs and medication-induced sleep problems are
Exibir todos os documentos relacionados

Artigos

HPLC Analysis of Z-Drugs on Ascentis® Express ES-Cyano 2.0 μm

An rapid method for the siµLtaneous determination of the Z-drugs or sleep aids: zopiclone, zolpidem, and zaleplon is presented here. The need for greater analytical capacity and throughput for the analysis of sleep aid medicines (Z-drugs) in forensic toxicology laboratories can be met by the use of fast Ascentis Express 2.0 micron Fused Core UHPLC Columns.

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