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T0397

Sigma-Aldrich

L-Thyroxine sodium salt pentahydrate

γ-irradiated, powder, BioXtra, suitable for cell culture

Sinônimo(s):

3-[4-(4-Hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl]-L-alanine sodium salt, Sodium levothyroxine, T4

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About This Item

Fórmula linear:
HOC6H2I2OC6H2I2CH2CH(NH2)COONa · 5H2O
Número CAS:
6106-07-6
Peso molecular:
888.93
Beilstein:
5721845
Número CE:
200-221-4
Número MDL:
MFCD00149110
Código UNSPSC:
12352209
ID de substância PubChem:
24899887
NACRES:
NA.77

fonte biológica

synthetic (organic)

Nível de qualidade

200

esterilidade

γ-irradiated

linha de produto

BioXtra

Ensaio

≥98%

forma

powder

potência

5-50 ng/mL

técnica(s)

cell culture | mammalian: suitable

pf

207-210 (dec.) (lit.)

solubilidade

cell culture medium: 0.1 mg/mL
H2O: soluble

temperatura de armazenamento

−20°C

cadeia de caracteres SMILES

O.O.O.O.O.[Na+].N[C@@H](Cc1cc(I)c(Oc2cc(I)c(O)c(I)c2)c(I)c1)C([O-])=O

InChI

1S/C15H11I4NO4.Na.5H2O/c16-8-4-7(5-9(17)13(8)21)24-14-10(18)1-6(2-11(14)19)3-12(20)15(22)23;;;;;;/h1-2,4-5,12,21H,3,20H2,(H,22,23);;5*1H2/q;+1;;;;;/p-1/t12-;;;;;;/m0....../s1

chave InChI

JMHCCAYJTTWMCX-QWPJCUCISA-M

Informações sobre genes

mouse ... Cnr2(12802)
rat ... Cnr1(25248)

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Categorias relacionadas

Ações bioquímicas/fisiológicas

L-Thyroxine (T4) and triiodo-L-thyronine (T3) are iodine-containing hormones produced from thyroglobulin in the thyroid follicular cells. The stimulation of metabolic rate and regulation of growth and development by these hormones appear to be due to their effects on DNA transcription and thus, protein synthesis.

forma física

powder-0 °C; stock-frozen in working aliquots, avoid repeated freeze/thaw, solution stable 2-8 °C, 30 days

Reconstituição

To prepare 20 μg/ml stock solution, add 50 ml sterile culture medium.

Pictogramas

Health hazard
GHS08

Palavra indicadora

Danger

Frases de perigo

H372

Declarações de precaução

P260 - P264 - P270 - P314 - P501

Classificações de perigo

STOT RE 1

Órgãos-alvo

Thyroid,Cardio-vascular system,Kidney

Código de classe de armazenamento

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

Equipamento de proteção individual

Eyeshields, Gloves, type N95 (US)

Certificados de análise (COA)

Busque Certificados de análise (COA) digitando o Número do Lote do produto. Os números de lote e remessa podem ser encontrados no rótulo de um produto após a palavra “Lot” ou “Batch”.

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