SRP8048

PEDF mouse

recombinant, expressed in CHO cells, FLAG^® tagged, >95% (SDS-PAGE)

• Sinônimo(s): Caspin, PC cell-derived growth factor, Pigment epithelium-derived factor, Stromal cell-derived factor 3
• Número CAS: 607410-75-3
• Código UNSPSC: 12352202
• NACRES: NA.32

Propriedades

• fonte biológica: mouse
• recombinante: expressed in CHO cells
• etiqueta: FLAG^® tagged
• Ensaio: >95% (SDS-PAGE)
• forma: lyophilized
• peso molecular: ~47 kDa by SDS-PAGE
• embalagem: pkg of 10 μg
• condição de armazenamento: avoid repeated freeze/thaw cycles
• Impurezas: <0.01 EU/μg endotoxin, tested
• cor: white
• nº de adesão UniProt: P97298
• Condições de expedição: wet ice
• temperatura de armazenamento: −20°C
• Informações sobre genes: mouse ... Serpinf1(20317)

Descrição

Descrição geral

Pigment epithelium-derived factor (PEDF) is a 47kDa secreted glycoprotein that belongs to the non-inhibitory serpin family group. PEDF is widely expressed in adult and fetal tissues, including brain, spinal cord, plasma, bone, prostate, pancreas, heart and lung. PEDF acts as an angiogenesis inhibitor with neurotrophic, immunomodulation and antitumor properties. It functions as anti-angiogenic agent by counterbalancing the proangiogenic effect of VEGF. PEDF is one of the most abundant proteins released by adipocytes and induces insulin resistance in adipocytes and human skeletal muscle cells. Recently, it has been reported that PEDF is sufficient to maintain the self-renewal of pluripotent human embryonic stem cells.

forma física

Lyophilized from PBS.

Reconstituição

Reconstitute with 100 μL deionized water.

Outras notas

Mouse PEDF (aa 20-417) is fused at the C-terminus to a FLAG^®-tag.

Informações legais

FLAG is a registered trademark of Merck KGaA, Darmstadt, Germany

Informações de segurança

• Código de classe de armazenamento: 10 - Combustible liquids
• Classe de risco de água (WGK): WGK 2
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable