SRP0172

Jak2 Jh1Jh2 Active human

recombinant, expressed in baculovirus infected insect cells, ≥70% (SDS-PAGE)

• Sinônimo(s): JAK2, JTK10, Janus kinase 2, Just another kinase 2, Tyrosine-protein kinase JAK2
• Código UNSPSC: 12352200
• NACRES: NA.32

Propriedades

• fonte biológica: human
• recombinante: expressed in baculovirus infected insect cells
• Ensaio: ≥70% (SDS-PAGE)
• Formulário: aqueous solution
• peso molecular: 99 kDa
• embalagem: pkg of 10 μg
• concentração: >0.02 mg/mL
• nº de adesão NCBI: NM_004972
• nº de adesão UniProt: O60674
• Condições de expedição: dry ice
• temperatura de armazenamento: −70°C
• Informações sobre genes: human ... JAK2(3717)

Descrição

Descrição geral

Human Jak2 (GenBank Accession No. NM_004972), containing the catalytic and the pseudo kinase domain (amino acids 532-1132) with N-terminal GST-His tag, MW = 99 kDa, expressed in a Baculovirus infected Sf9 cell expression system.

Aplicação

Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling

Definição da unidade

One unit is defined as the amount of enzyme that will phosphorylate 1 nmol of tyrosine substrate per minute at pH 7.4 and 30°C.

forma física

Formulated in 25 mM Tris-HCl, pH 8.0, 100 mM NaCl, 0.05% Tween-20, 50% glycerol and 3 mM DTT.

Nota de preparo

Thaw on ice. Upon first thaw, briefly spin tube containing enzyme to recover full content of the tube. Aliquot enzyme into single use aliquots. Store remaining undiluted enzyme in aliquots at -70°C. Note: Enzyme is very sensitive to freeze/thaw cycles.

Informações de segurança

• Código de classe de armazenamento: 12 - Non Combustible Liquids
• Classe de risco de água (WGK): WGK 1
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable