SML1236

(−)-Nicotine hydrogen tartrate salt

≥98% (HPLC)

• Sinônimo(s): (−)-Nicotine ditartrate, (−)-1-Methyl-2-(3-pyridyl)pyrrolidine (+)-bitartrate salt
• Fórmula empírica (Notação de Hill): C₁₀H₁₄N₂ · 2C₄H₆O₆
• Número CAS: 65-31-6
• Peso molecular: 462.41
• Número CE: 200-607-2
• Código UNSPSC: 12352210
• ID de substância PubChem: 329825736
• NACRES: NA.77

Propriedades

• Nível de qualidade: 100
• Ensaio: ≥98% (HPLC)
• Formulário: powder
• atividade óptica: [α]/D +20 to +26°, c = 1.0 in water
• condição de armazenamento: desiccated
• cor: white to beige
• solubilidade: H₂O: 20 mg/mL, clear
• temperatura de armazenamento: room temp
• cadeia de caracteres SMILES: CN1CCC[C@H]1C2=CC=CN=C2.C
• InChI: 1S/C10H14N2.CH4/c1-12-7-3-5-10(12)9-4-2-6-11-8-9;/h2,4,6,8,10H,3,5,7H2,1H3;1H4/t10-;/m0./s1
• chave InChI: RYYKFQGHMYGLEL-PPHPATTJSA-N

Descrição

Aplicação

(−)-Nicotine hydrogen tartrate salt has been used as an agonist for acetylcholine receptor (AChr).

(−)-Nicotine hydrogen tartrate salt has been used in intracellular calcium imaging.

Ações bioquímicas/fisiológicas

NHT is considered to be more stable than nicotine. Nicotine is highly addictive drug and is indirectly but strongly associated with tobacco related diseases. It helps to discontinue smoking. Nicotine might serve as a therapeutic agent in treating Alzheimer’s disease, Parkinson’s disease and ulcerative colitis.

Prototype nicotinic acetylcholine receptor agonist; naturally occurring isomer.

Informações de segurança

• Pictogramas: GHS06,GHS08,GHS09
• Palavra indicadora: Danger
• Frases de perigo: H301,H319,H330,H361d,H411
• Declarações de precaução: P202 - P260 - P264 - P273 - P304 + P340 + P310 - P305 + P351 + P338
• Classificações de perigo: Acute Tox. 2 Inhalation - Acute Tox. 3 Oral - Aquatic Chronic 2 - Eye Irrit. 2 - Repr. 2
• Código de classe de armazenamento: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• Classe de risco de água (WGK): WGK 2
• Ponto de fulgor (°F): 289.8 °F
• Ponto de fulgor (°C): 143.2 °C