SML0243

ML169

≥98% (HPLC)

• Sinônimo(s): 2-[[1-[(5-Bromo-2-fluorophenyl)methyl]-1H-indol-3-yl]sulfonyl]-N-(5-methyl-3-isoxazolyl)-acetamide, VU0405652
• Fórmula empírica (Notação de Hill): C₂₁H₁₇BrFN₃O₄S
• Número CAS: 1222878-02-5
• Peso molecular: 506.34
• Número MDL: MFCD23704785
• Código UNSPSC: 12352200
• ID de substância PubChem: 329825253
• NACRES: NA.77

Propriedades

• Ensaio: ≥98% (HPLC)
• Formulário: powder
• cor: white to beige
• solubilidade: DMSO: >5 mg/mL
• temperatura de armazenamento: 2-8°C
• cadeia de caracteres SMILES: Cc1cc(NC(=O)CS(=O)(=O)c2cn(Cc3cc(Br)ccc3F)c4ccccc24)no1
• InChI: 1S/C21H17BrFN3O4S/c1-13-8-20(25-30-13)24-21(27)12-31(28,29)19-11-26(18-5-3-2-4-16(18)19)10-14-9-15(22)6-7-17(14)23/h2-9,11H,10,12H2,1H3,(H,24,25,27)
• chave InChI: RUYRNYRGPSAXTK-UHFFFAOYSA-N

Descrição

Ações bioquímicas/fisiológicas

ML169 is a positive allosteric modulator (PAM) of the muscarinic acetylcholine receptor M1 (CHRM1). ML169 does not cross react with other muscarinic receptors and is able to penetrate the blood brain barrier.

ML169 is a positive allosteric modulator of muscarinic acetylcholine receptor M1.

Características e benefícios

This compound is a featured product for Neuroscience research. Click here to discover more featured Neuroscience products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

This compound is featured on the Acetylcholine Receptors (Muscarinic) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Informações de segurança

• Código de classe de armazenamento: 11 - Combustible Solids
• Classe de risco de água (WGK): WGK 3
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable