SMB01064

Dimethylfraxetin

≥90% (LC/MS-ELSD)

• Sinônimo(s): 6,7,8,-trimethoxycoumarin, 6,7,8-trimethoxychromen-2-one, Fraxidin Methyl Ether
• Fórmula empírica (Notação de Hill): C₁₂H₁₂O₅
• Número CAS: 6035-49-0
• Peso molecular: 236.22
• Número MDL: MFCD00145039
• Código UNSPSC: 12352205
• NACRES: NA.25

Propriedades

• fonte biológica: plant
• Ensaio: ≥90% (LC/MS-ELSD)
• Formulário: solid
• peso molecular: 236.22
• aplicação(ões): metabolomics; vitamins, nutraceuticals, and natural products
• temperatura de armazenamento: −20°C
• cadeia de caracteres SMILES: [o]1c2c(cc[c]1=O)cc(c(c2OC)OC)OC
• InChI: 1S/C12H12O5/c1-14-8-6-7-4-5-9(13)17-10(7)12(16-3)11(8)15-2/h4-6H,1-3H3
• chave InChI: RAYQKHLZHPFYEJ-UHFFFAOYSA-N

Descrição

Descrição geral

Dimethylfraxetin, also known as 6,7,8-Trimethoxycoumarin, a coumarin derivative, is a natural product commonly found in Pittosporum illicioides, Garcinia multiflora, and Cryptocarya bracteolata. It exhibits a range of biological activities, including anti-inflammatory, antioxidant, anticancer, and antimicrobial properties.

Aplicação

It is a natural product derived from plant source that finds application in compound screening libraries, metabolomics, phytochemical and biochemical research.

Ações bioquímicas/fisiológicas

• Binds to the CB2 receptor and induces immunomodulatory effects.
• Exhibits anti-inflammatory properties by inhibiting prostaglandin synthesis in the human erythroleukemia cell line K562.
• Inhibits the replication of both DNA and RNA.
• Blocks aminoacyl-tRNA binding to ribosomes, inhibiting protein synthesis.
• Binds to phenolic acid receptors on cultured cells.

Características e benefícios

• High quality compound suitable for multiple research applications
• Compatible with HPLC and mass spectrometry techniques

Outras notas

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Informações de segurança

• Pictogramas: GHS07
• Palavra indicadora: Warning
• Frases de perigo: H302
• Declarações de precaução: P264 - P270 - P301 + P312 - P501
• Classificações de perigo: Acute Tox. 4 Oral
• Código de classe de armazenamento: 11 - Combustible Solids
• Classe de risco de água (WGK): WGK 3
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable