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SMB01013

Sigma-Aldrich

Methyl 2,5-Dihydroxycinnamate

≥90% (LC/MS-ELSD)

Sinônimo(s):

2,4-Dihydroxymethylcinnamate, Methyl grevillate

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About This Item

Fórmula empírica (Notação de Hill):
C10H10O4
Número CAS:
Peso molecular:
194.18
Número MDL:
Código UNSPSC:
12352205
NACRES:
NA.25

fonte biológica

plant

Ensaio

≥90% (LC/MS-ELSD)

forma

solid

peso molecular

194.18

solubilidade

water: slightly soluble

aplicação(ões)

metabolomics
vitamins, nutraceuticals, and natural products

temperatura de armazenamento

−20°C

InChI

1S/C10H10O4/c1-14-10(13)5-2-7-6-8(11)3-4-9(7)12/h2-6,11-12H,1H3

chave InChI

BQCNSTFWSKOWMA-UHFFFAOYSA-N

Descrição geral

Methyl 2,5-dihydroxycinnamate, a hydroxycinnamic acid, is a bioactive natural compound commonly derived from plants like Azadirachta indica and Murraya paniculata. Current research indicates that this plant-derived metabolite may possess diverse biological activities, encompassing anti-inflammatory and antitumor properties. Furthermore, it serves as a human urinary metabolite, a geroprotector, and an inhibitor of EC 2.7.10.1 (receptor protein-tyrosine kinase). It is a cell-permeable analog of erbstatin, a natural substance found in Streptomyces, demonstrates inhibitory effects on the autophosphorylation of the epidermal growth factor receptor. Moreover, it acts as a competitive inhibitor of epidermal growth factor receptor-associated tyrosine kinase, effectively impeding v-abl tyrosine kinase activation. Additionally, Methyl 2,5-dihydroxycinnamate has been observed to induce apoptosis in mouse thymocytes and inhibit the G2/M phase of the cell cycle.

Aplicação

Methyl 2,5-Dihydroxycinnamate is a natural product derived from plant source that finds application in compound screening libraries, metabolomics, phytochemical, and pharmaceutical research.

Características e benefícios

  • Suitable for Biochemical and Biomedical research
  • Versatile and adaptable for wide variety of laboratory and research applications

Outras notas

For additional information on our range of Biochemicals, please complete this form.

Código de classe de armazenamento

11 - Combustible Solids

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable


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