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Documentos Principais

SMB00110

Sigma-Aldrich

Plumieride

≥95% (LC/MS-ELSD)

Sinônimo(s):

Agoniadin

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About This Item

Fórmula empírica (Notação de Hill):
C21H26O12
Número CAS:
Peso molecular:
470.42
Código UNSPSC:
12352205
ID de substância PubChem:
NACRES:
NA.25

Ensaio

≥95% (LC/MS-ELSD)

forma

solid

aplicação(ões)

metabolomics
vitamins, nutraceuticals, and natural products

temperatura de armazenamento

−20°C

cadeia de caracteres SMILES

COC(=O)C1=CO[C@@H](O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)[C@H]3[C@@H]1C=C[C@]34OC(=O)C(=C4)[C@H](C)O

InChI

1S/C21H26O12/c1-8(23)10-5-21(33-18(10)28)4-3-9-11(17(27)29-2)7-30-19(13(9)21)32-20-16(26)15(25)14(24)12(6-22)31-20/h3-5,7-9,12-16,19-20,22-26H,6H2,1-2H3/t8-,9+,12+,13+,14+,15-,16+,19-,20-,21+/m0/s1

chave InChI

AOPMSFXOYJXDNJ-IRFSQMTFSA-N

Descrição geral

Natural product derived from plant source.

Código de classe de armazenamento

11 - Combustible Solids

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable


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Mahabeer P Dobhal et al.
The Journal of organic chemistry, 69(19), 6165-6172 (2004-09-11)
Plumieride was isolated as one of the major components from the biologically active methanolic extract of the bark of Plumeria bicolor (family Apocynaceae). For investigating the effect of substituents on cytotoxic activity it was modified into a series of compounds.
M S Abdel-Kader et al.
Journal of natural products, 60(12), 1294-1297 (1998-01-15)
Bioassay-guided fractionation of the EtOAc extract of both Allamanda cathartica and Himatanthus fallax (Apocynaceae) using the Sc-7 yeast strain resulted in the isolation of the weakly cytotoxic isoplumericin and plumericin. In addition, the new lignan 7(R)-methoxy-8-epi-matairesional and three known compounds
T N Tiwari et al.
Phytotherapy research : PTR, 16(4), 393-394 (2002-07-12)
Plumieride has been isolated as an active principle of the leaves of Allamanda cathartica. It showed strong fungitoxicity against some dermatophytes causing dermatomycosis to animals and human beings. It exhibited a noncytotoxic nature against a P(388) mouse leukaemia cell line.
R S Gupta et al.
Phytomedicine : international journal of phytotherapy and phytopharmacology, 11(2-3), 169-174 (2004-04-09)
Oral feeding of male rats with plumieride (15 mg/rat/day) for the period of 60 days did not cause any significant change in the body weight of treated rats. However, the weights of testes, epididymides, seminal vesicle and ventral prostate were
Sebastião de O Rebouças et al.
Journal of ethnopharmacology, 147(2), 474-480 (2013-03-27)
Himatanthus articulatus (Apocynaceae) is a plant native to the Amazon, popularly used to treat external ulcers, tumors, inflammations, cancer, syphilis and malaria. To investigate the in vivo genotoxic and mutagenic potential of this plant, using the comet assay and the

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