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Merck
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Key Documents

SCP0059

Sigma-Aldrich

Calcitonin Acetyl salmon

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About This Item

Fórmula empírica (Notação de Hill):
C147H242N44O49S2
Peso molecular:
3473.89
Código UNSPSC:
51111800
NACRES:
NA.77

Ensaio

≥95% (HPLC)

forma

lyophilized

composição

Peptide Content, ≥75%

condição de armazenamento

protect from light

temperatura de armazenamento

−20°C

Amino Acid Sequence

Ac-Cys-Ser-Asn-Leu-Ser-Thr-Cys-Val-Leu-Gly-Lys-Leu-Ser-Gln-Glu-Leu-His-Lys-Leu-Gln-Thr-Tyr-Pro-Arg-Thr-Asn-Thr-Gly-Ser-Gly-Thr-Pro-NH2

Aplicação

Calcitonin, a 32 amino acid polypeptide, is involved in the regulation of calcium and phosphorous metabolism often antagonistic to parathyroid hormone (PTH).

Pictogramas

Skull and crossbones

Palavra indicadora

Danger

Frases de perigo

Declarações de precaução

Classificações de perigo

Acute Tox. 3 Oral

Código de classe de armazenamento

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

Classe de risco de água (WGK)

WGK 3


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Synthesis, characterization and evaluation of bone targeting salmon calcitonin analogs in normal and osteoporotic rats.
Bhandari KH, Newa M, Chapman J, et al.
J. Controlled Release, 158, 44-52 (2012)
Claudia Mueller et al.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 79(3), 646-657 (2011-06-28)
Protein aggregation, which is triggered by various factors, is still one of the most prevalent problems encountered during all stages of protein formulation development. In this publication, we present novel excipients, tryptophan-mPEGs (Trp-mPEGs) of 2 and 5 kDa molecular weight
Aiwen Huang et al.
Drug delivery, 18(8), 562-569 (2011-08-10)
Therapeutic peptide and protein drugs have high specificity and activity in their functions but present challenges in their administration route, requiring development of new delivery systems to improve their bioavailability. The aim of this work was to investigate the role
Cetin Tas et al.
International journal of pharmaceutics, 423(2), 257-263 (2011-12-17)
Peptides and polypeptides have important pharmacological properties but only a limited number have been exploited as therapeutics because of problems related to their delivery. Most of these drugs require a parenteral delivery system which introduces the problems of pain, possible

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