SAB5701107

Anti-Amyloid Precursor Protein (APP) Antibody

rabbit monoclonal

• Código UNSPSC: 12352203
• NACRES: NA.43

Propriedades

• Nome do produto: Anti- APP antibody produced in rabbit,
• fonte biológica: rabbit
• Nível de qualidade: 100
• tipo de produto de anticorpo: primary antibodies
• clone: monoclonal
• Formulário: liquid
• reatividade de espécies: human, rat, mouse
• concentração: 0.93 mg/mL
• técnica(s): western blot: 1:500-1:2000
• nº de adesão UniProt: P05067
• Condições de expedição: wet ice
• temperatura de armazenamento: −20°C
• modificação pós-traducional do alvo: unmodified
• Informações sobre genes: human ... APP(351)

Descrição

Descrição geral

This gene encodes a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation, while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease. In addition, two of the peptides are antimicrobial peptides, having been shown to have bacteriocidal and antifungal activities. Mutations in this gene have been implicated in autosomal dominant Alzheimer disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy). Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq, Aug 2014]

Imunogênio

A synthesized peptide derived from human APP

forma física

Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.

Informações de segurança

• Código de classe de armazenamento: 12 - Non Combustible Liquids
• Classe de risco de água (WGK): WGK 1
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable