SAB5700454

Anti-Phospho-FLNA-S2152 antibody produced in rabbit

• Sinônimo(s): ABP-280, ABPX, CSBS, CVD1, FLN, FLN-A, FLN1, FLNA, FMD, MNS, NHBP, OPD, OPD1, OPD2, XLVD, XMVD, filamin-A
• Código UNSPSC: 12352203
• NACRES: NA.41

Propriedades

• fonte biológica: rabbit
• Nível de qualidade: 100
• forma do anticorpo: affinity isolated antibody
• tipo de produto de anticorpo: primary antibodies
• clone: polyclonal
• Formulário: buffered aqueous solution
• peso molecular: 280
• reatividade de espécies: rat, mouse, human
• concentração: 1.7 mg/ml
• técnica(s): western blot: 1:500-1:2000
• nº de adesão UniProt: P21333
• Condições de expedição: wet ice
• temperatura de armazenamento: −20°C
• modificação pós-traducional do alvo: phosphorylation (pSer2152)
• Informações sobre genes: human ... FLNA(2316)

Descrição

Descrição geral

The protein encoded by this gene is an actin-binding protein that crosslinks actin filaments and links actin filaments to membrane glycoproteins. The encoded protein is involved in remodeling the cytoskeleton to effect changes in cell shape and migration. This protein interacts with integrins, transmembrane receptor complexes, and second messengers. Defects in this gene are a cause of several syndromes, including periventricular nodular heterotopias (PVNH1, PVNH4), otopalatodigital syndromes (OPD1, OPD2), frontometaphyseal dysplasia (FMD), Melnick-Needles syndrome (MNS), and X-linked congenital idiopathic intestinal pseudoobstruction (CIIPX). Two transcript variants encoding different isoforms have been found for this gene.

Imunogênio

A synthetic phosphorylated peptide around S2152 of human FLNA (NP_001104026.1).

forma física

PBS with 0.02% sodium azide,50% glycerol,pH7.3.

Armazenamento e estabilidade

Store at -20℃. Avoid freeze / thaw cycles.

Informações de segurança

• Código de classe de armazenamento: 12 - Non Combustible Liquids
• Classe de risco de água (WGK): WGK 1
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable