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Documentos Principais

SAB4503944

Sigma-Aldrich

Anti-phospho-MYPT1 (pThr853) antibody produced in rabbit

affinity isolated antibody

Sinônimo(s):

Anti-phospho-MYPT1, Phospho-MYPT1 Detection, Rabbit Anti-MYPT1

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About This Item

Código UNSPSC:
12352203
NACRES:
NA.43

fonte biológica

rabbit

Nível de qualidade

100

conjugado

unconjugated

forma do anticorpo

affinity isolated antibody

tipo de produto de anticorpo

primary antibodies

clone

polyclonal

Formulário

buffered aqueous solution

peso molecular

antigen 115 kDa

reatividade de espécies

human, mouse, rat

concentração

~1 mg/mL

técnica(s)

ELISA: 1:1000
immunohistochemistry: 1:50-1:100
western blot: 1:500-1:1000

nº de adesão NCBI

O14974

nº de adesão UniProt

O14974

Condições de expedição

wet ice

temperatura de armazenamento

−20°C

modificação pós-traducional do alvo

phosphorylation (pThr853)

Informações sobre genes

human ... PPP1R12A(4659)

Imunogênio

The antiserum was produced against synthesized peptide derived from human MYPT1 around the phosphorylation site of Thr853.

Immunogen Range: 621-670

Características e benefícios

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

forma física

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Exoneração de responsabilidade

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Código de classe de armazenamento

10 - Combustible liquids

Classe de risco de água (WGK)

WGK 1

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

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Certificados de análise (COA)

Lot/Batch Number
109170518
110518

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Corey A Smith et al.
Frontiers in physiology, 8, 681-681 (2017-09-26)
Metabolic stress diminishes smooth muscle contractile strength by a poorly defined mechanism. To test the hypothesis that metabolic stress activates a compensatory cell signaling program to reversibly downregulate contraction, arterial rings and bladder muscle strips
Claudio Cantin et al.
Current vascular pharmacology, 18(1), 87-91 (2019-01-22)
Angiotensin II is a potent activator of the Rho-kinase (ROCK) pathway, through which it exerts some of its adverse vasoconstrictor effects. Clinical evidence on the effects of blocking the angiotensin II receptor 1 on ROCK activity in hypertensive patients is
Feng Liu et al.
Kidney & blood pressure research, 43(5), 1425-1436 (2018-09-14)
Endothelial-to-mesenchymal transition (EndMT) of glomerular endothelial cells (GEnCs) can induce albuminuria in diabetic nephropathy. Melatonin attenuates diabetic nephropathy, but its role and mechanism in EndMT of GEnCs in diabetic nephropathy remain unknown. The effect of melatonin on EndMT induced by
Leily Kashkooli et al.
PLoS biology, 19(1), e3001060-e3001060 (2021-01-07)
Collective migration of cohesive tissues is a fundamental process in morphogenesis and is particularly well illustrated during gastrulation by the rapid and massive internalization of the mesoderm, which contrasts with the much more modest movements of the ectoderm. In the
Juhyun Park et al.
PloS one, 12(2), e0172751-e0172751 (2017-03-01)
The efficacy of statins is related to the 'common soil' hypothesis, which proposes oxidative stress and inflammation as main pathophysiologic processes in the disease group of diabetes and endothelial dysfunction. This study evaluated the recovery of erectile function after administration
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