SAB4500418

Anti-GPR151 antibody produced in rabbit

affinity isolated antibody

• Sinônimo(s): G-protein coupled receptor PGR7, GPCR-2037, GPR151, PGR7, Probable G-protein coupled receptor 151
• Código UNSPSC: 12352203
• NACRES: NA.41

Propriedades

• fonte biológica: rabbit
• Nível de qualidade: 100
• conjugado: unconjugated
• forma do anticorpo: affinity isolated antibody
• tipo de produto de anticorpo: primary antibodies
• clone: polyclonal
• Formulário: buffered aqueous solution
• peso molecular: antigen 46 kDa
• reatividade de espécies: rat, human, mouse
• concentração: ~1 mg/mL
• técnica(s): ELISA: 1:1000; immunofluorescence: 1:100-1:500; western blot: 1:500-1:1000
• nº de adesão NCBI: Q8TDV0
• Condições de expedição: wet ice
• temperatura de armazenamento: −20°C
• modificação pós-traducional do alvo: unmodified
• Informações sobre genes: human ... GPR151(134391)

Descrição

Descrição geral

G protein-coupled receptor 151 (GPR151) is encoded by the gene mapped to human chromosome 5. It belongs to the A type of G protein-coupled receptor (GPCR) family and it shows homology with galanin receptor 2 and 3. In mice, GPR151 transcript is highly and specifically expressed in habenular neurons.

Imunogênio

The antiserum was produced against synthesized peptide derived from human GPR151.

Immunogen Range: 370-419

Aplicação

Anti-GPR151, C-Terminal antibody produced in rabbit has been used for Western blotting.

Ações bioquímicas/fisiológicas

G protein-coupled receptor 151 (GPR151) is a highly conserved protein, and acts as a potential target for psychiatric drug development, due to its expression in habenular neurons which may be critically involved in the pathophysiology of psychiatric disorders such as addiction and depression. Experimental studies reveal that GPR151 might play a neuroprotective and/or pro-regenerative role in the dorsal root ganglion (DRG) after nerve injury.

Características e benefícios

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forma física

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Exoneração de responsabilidade

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informações de segurança

• Código de classe de armazenamento: 12 - Non Combustible Liquids
• Classe de risco de água (WGK): nwg
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable