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Key Documents

SAB4300959

Sigma-Aldrich

Anti-CTSL antibody produced in rabbit

affinity isolated antibody

Sinônimo(s):

CATL, CTSL1, MEP

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About This Item

Código UNSPSC:
12352203
NACRES:
NA.41

fonte biológica

rabbit

Nível de qualidade

100

forma do anticorpo

affinity isolated antibody

tipo de produto de anticorpo

primary antibodies

clone

polyclonal

forma

buffered aqueous solution

peso molecular

38 kDa

reatividade de espécies

mouse, human

concentração

1.8 mg/mL

técnica(s)

immunohistochemistry: 1:50- 1:200
western blot: 1:500-1:2000 (Cell Lysate)

Isotipo

IgG

nº de adesão

NP_001244900.1

nº de adesão UniProt

P07711

Condições de expedição

wet ice

temperatura de armazenamento

−20°C

modificação pós-traducional do alvo

unmodified

Informações sobre genes

human ... CTSL(1514)

Especificidade

The antibody detects endogenous levels of total CTSL protein.

Imunogênio

Fusion protein corresponding to a region derived from internal residues of human cathepsin L

Características e benefícios

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

forma física

Rabbit IgG in pH7.3 PBS, 0.05% NaN3, 50% Glycerol.

Exoneração de responsabilidade

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Nº do produto
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Código de classe de armazenamento

10 - Combustible liquids

Classe de risco de água (WGK)

WGK 1

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

Certificados de análise (COA)

Busque Certificados de análise (COA) digitando o Número do Lote do produto. Os números de lote e remessa podem ser encontrados no rótulo de um produto após a palavra “Lot” ou “Batch”.

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Guo-Xiang Fu et al.
Free radical research, 51(11-12), 932-942 (2017-10-19)
Recent evidence suggests a link between cathepsin L (CTSL) and vascular diseases. However, its contribution to reactive oxygen species (ROS) homeostasis in the vasculature remains unknown. p66shc is a redox enzyme implicated in mitochondrial ROS generation and translation of oxidative
Xinya Xu et al.
Journal of dermatological science, 90(3), 263-275 (2018-03-05)
The deposition of advanced glycation end products (AGEs) is accelerated in photoaged skin, but the underlying mechanisms remain elusive. Intracellular degradation has been recently considered to play an important role in AGEs removal. Although lysosomal cathepsin D (CatD), B (CatB)
Annika K Hult et al.
Transfusion, 58(8), 2036-2045 (2018-10-03)
The FORS histo-blood group system was described in 2013 and much remains to be investigated regarding its genetic and immunohematologic characteristics, as well as its clinical importance. While presence of the c.887G>A-mutated GBGT1 gene, which results in FORS1 glycosphingolipid expression
Mike Flint et al.
Nature communications, 10(1), 285-285 (2019-01-19)
There are no approved therapies for Ebola virus infection. Here, to find potential therapeutic targets, we perform a screen for genes essential for Ebola virus (EBOV) infection. We identify GNPTAB, which encodes the α and β subunits of N-acetylglucosamine-1-phosphate transferase.
Chris W Lee et al.
Molecular neurodegeneration, 12(1), 55-55 (2017-07-27)
Haploinsufficiency of GRN, the gene encoding progranulin (PGRN), causes frontotemporal lobar degeneration (FTLD), the second most common cause of early-onset dementia. Receptor-mediated lysosomal targeting has been shown to regulate brain PGRN levels, and complete deficiency of PGRN is a direct
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