SAB4300684

Anti-phospho-Cyclin E1 (pThr³⁹⁵) antibody produced in rabbit

affinity isolated antibody

• Sinônimo(s): Anti-CCNE, Anti-CCNE1
• Código UNSPSC: 12352203
• NACRES: NA.41

Propriedades

• fonte biológica: rabbit
• Nível de qualidade: 100
• conjugado: unconjugated
• forma do anticorpo: affinity isolated antibody
• tipo de produto de anticorpo: primary antibodies
• clone: polyclonal
• forma: buffered aqueous solution
• peso molecular: ~48 kDa
• reatividade de espécies: human
• concentração: 1 mg/mL
• técnica(s): western blot: 1:500-1:1000
• Isotipo: IgG
• sequência de imunogênio: (L-L-Tp-P-P)
• nº de adesão NCBI: NM_001238.1
• Condições de expedição: wet ice
• temperatura de armazenamento: −20°C
• modificação pós-traducional do alvo: phosphorylation (pThr395)
• Informações sobre genes: human ... CCNE1(898)

Descrição

Descrição geral

The antibody detects endogenous level of Cyclin E1 only when phosphorylated at threonine 395.

Imunogênio

Peptide sequence around phosphorylation site of threonine 395 (L-L-Tp-P-P), according to the protein NP_001229.1

Características e benefícios

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Descrição-alvo

The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK2, whose activity is required for cell cycle G1/S transition.

forma física

Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol

Informações de segurança

• Código de classe de armazenamento: 10 - Combustible liquids
• Classe de risco de água (WGK): WGK 1
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable