SAB4300139

Anti-phospho-SNCA (pSer¹²⁹) antibody produced in rabbit

affinity isolated antibody

• Sinônimo(s): Anti-MGC110988 antibody produced in rabbit, Anti-NACP antibody produced in rabbit, Anti-PARK1 antibody produced in rabbit, Anti-PARK4 antibody produced in rabbit, Anti-synuclein, alpha (non A4 component of amyloid precursor) antibody produced in rabbit
• Número MDL: MFCD02095740
• Código UNSPSC: 12352203
• NACRES: NA.41

Propriedades

• fonte biológica: rabbit
• conjugado: unconjugated
• forma do anticorpo: affinity isolated antibody
• tipo de produto de anticorpo: primary antibodies
• clone: polyclonal
• Formulário: buffered aqueous solution
• peso molecular: ~18 kDa
• reatividade de espécies: mouse, rat, human
• concentração: 1 mg/mL
• técnica(s): western blot: 1:500-1:1000
• Isotipo: IgG
• sequência de imunogênio: (M-P-SP-E-E)
• nº de adesão NCBI: NP_000336.1
• nº de adesão UniProt: P37840
• Condições de expedição: wet ice
• temperatura de armazenamento: −20°C
• modificação pós-traducional do alvo: phosphorylation (pSer129)
• Informações sobre genes: human ... SNCA(6622)

Descrição

Imunogênio

Peptide sequence around phosphorylation site of serine 129 (M-P-S(p)-E-E), according to the protein SNCA.

Características e benefícios

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Descrição-alvo

May be involved in the regulation of dopamine release and transport. Soluble protein, normally localized primarily at the presynaptic region of axons, which can form filamentous aggregates that are the major non amyloid component of intracellular inclusions in several neurodegenerative diseases (synucleinopathies). Induces fibrillization of microtubule-associated protein tau. Reduces neuronal responsiveness to various apoptotic stimuli, leading to a decreased caspase-3 activation.

forma física

Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol

Exoneração de responsabilidade

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informações de segurança

• Código de classe de armazenamento: 10 - Combustible liquids
• Classe de risco de água (WGK): WGK 1
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable