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Merck
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Key Documents

SAB2500895

Sigma-Aldrich

Anti-RPE65 antibody produced in goat

affinity isolated antibody, buffered aqueous solution

Sinônimo(s):

Anti-LCA2, Anti-RP20, Anti-Rd12, Anti-Retinal pigment epithelium-specific protein 65 kDa, Anti-SRPE65

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About This Item

Código UNSPSC:
12352203
NACRES:
NA.41

fonte biológica

goat

conjugado

unconjugated

forma do anticorpo

affinity isolated antibody

tipo de produto de anticorpo

primary antibodies

clone

polyclonal

forma

buffered aqueous solution

reatividade de espécies

human, canine

técnica(s)

indirect ELISA: suitable
western blot: suitable

nº de adesão UniProt

Condições de expedição

dry ice

temperatura de armazenamento

−20°C

modificação pós-traducional do alvo

unmodified

Informações sobre genes

human ... RPE65(6121)

Categorias relacionadas

Imunogênio

Peptide with sequence C-EVKKNARKAPQPE from the internal region of the protein sequence according to NP_000320.1.

Características e benefícios

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

forma física

Supplied at 0.5 mg/mL in Tris saline with 0.02% sodium azide and 0.5% bovine serum albumin.

Exoneração de responsabilidade

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Pictogramas

Exclamation mark

Palavra indicadora

Warning

Frases de perigo

Declarações de precaução

Classificações de perigo

Eye Irrit. 2 - Skin Irrit. 2

Código de classe de armazenamento

10 - Combustible liquids

Classe de risco de água (WGK)

WGK 2

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable


Certificados de análise (COA)

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Xueting Luo et al.
Disease models & mechanisms, 11(4) (2018-04-07)
Subretinal fibrosis results in local destruction of retinal structures and permanent vision loss, representing the end stage of neovascular age-related macular degeneration (AMD). Histological examination of fibrotic specimens from AMD patients has uncovered a wide range of cellular and acellular
Hiba Amer Alsaeedi et al.
Journal of photochemistry and photobiology. B, Biology, 198, 111561-111561 (2019-07-29)
Blindness and vision loss contribute to irreversible retinal degeneration, and cellular therapy for retinal cell replacement has the potential to treat individuals who have lost light sensitive photoreceptors in the retina. Retinal cells are well characterized in function, and are
Giorgia Fanelli et al.
Scientific reports, 7(1), 14625-14625 (2017-11-09)
Age-related macular degeneration (AMD) is a major cause of blindness and is associated with complement dysregulation. The disease is a potential target for stem cell therapy but success is likely to be limited by the inflammatory response. We investigated the
Rajalekshmy Shyam et al.
Proceedings of the National Academy of Sciences of the United States of America, 114(41), 10882-10887 (2017-09-07)
Carotenoids are plant-derived pigment molecules that vertebrates cannot synthesize de novo that protect the fovea of the primate retina from oxidative stress and light damage.
Xiaoping Qi et al.
Molecular therapy : the journal of the American Society of Gene Therapy, 25(4), 917-927 (2017-02-17)
Bone marrow stem and progenitor cells can differentiate into a range of non-hematopoietic cell types, including retinal pigment epithelium (RPE)-like cells. In this study, we programmed bone marrow-derived cells (BMDCs) ex vivo by inserting a stable RPE65 transgene using a lentiviral vector.

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