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SAB1305567

Sigma-Aldrich

MONOCLONAL ANTI-BETA-ACTIN antibody produced in mouse

clone 8H10D10, crude ascites, buffered aqueous solution

Sinônimo(s):

ACTB, Actin, cytoplasmic 1, Actin, cytoplasmic 1, N-terminally processed, Beta-actin

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About This Item

Código UNSPSC:
12352203
NACRES:
NA.41
clone:
8H10D10, monoclonal
application:
IHC
WB
reatividade de espécies:
human
técnica(s):
immunohistochemistry: 1:10-1:50
western blot: 1:5000-1:20000
citations:
19

fonte biológica

mouse

forma do anticorpo

crude ascites

tipo de produto de anticorpo

primary antibodies

clone

8H10D10, monoclonal

Formulário

buffered aqueous solution

peso molecular

41737 Da

reatividade de espécies

human

técnica(s)

immunohistochemistry: 1:10-1:50
western blot: 1:5000-1:20000

nº de adesão NCBI

nº de adesão UniProt

Condições de expedição

wet ice

temperatura de armazenamento

−20°C

modificação pós-traducional do alvo

unmodified

Informações sobre genes

human ... ACTB(60)

Descrição geral

ACTB (actin β) gene codes for β-actin. It is a cytoskeletal housekeeping protein. It is present in the cytoplasm. This gene is located on human chromosome 7p22.1.

Aplicação

MONOCLONAL ANTI-BETA-ACTIN antibody has been used in western blotting.

Ações bioquímicas/fisiológicas

β-Actin modulates cell growth, migration and the G-actin pool. Mutations in ACTB leads to pleiotropic developmental disorder.

forma física

Supplied in PBS with 0.09% (W/V) sodium azide

Exoneração de responsabilidade

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Código de classe de armazenamento

12 - Non Combustible Liquids

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable


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Radiation alters the cargo of exosomes released from squamous head and neck cancer cells to promote migration of recipient cells.
Mutschelknaus L, et al.
Scientific Reports, 7(1), 12423-12423 (2017)
Gabriela M Wright et al.
PloS one, 16(6), e0252927-e0252927 (2021-06-18)
Theoretically, small molecule CDK4/6 inhibitors (CDK4/6is) represent a logical therapeutic option in non-small cell lung cancers since most of these malignancies have wildtype RB, the key target of CDKs and master regulator of the cell cycle. Unfortunately, CDK4/6is are found
Lisa Mutschelknaus et al.
Scientific reports, 7(1), 12423-12423 (2017-10-01)
Radiation is a highly efficient therapy in squamous head and neck carcinoma (HNSCC) treatment. However, local recurrence and metastasis are common complications. Recent evidence shows that cancer-cell-derived exosomes modify tumour cell movement and metastasis. In this study, we link radiation-induced
Xinjun Lin et al.
Experimental and therapeutic medicine, 16(1), 204-212 (2018-06-14)
The present study aimed to evaluate the impact of dendrobium mixture (DMix) on the gene and protein expression of insulin signaling pathway-associated factors in the livers of diabetic rats. The molecular mechanisms by which DMix inhibits gluconeogenesis were also investigated.
Mengmeng Fan et al.
Oncology reports, 47(1) (2021-11-06)
The epithelial‑stromal interaction 1 gene (EPSTI1) is known to play multiple roles in the malignant progression of breast cancer and also in some aspects of the immune responses to the tumor. However, the relevance of the gene in the onset/progression

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