SAB1300765

Anti-PARP16 (C-term) antibody produced in rabbit

saturated ammonium sulfate (SAS) precipitated, buffered aqueous solution

• Sinônimo(s): Anti-EC 2.4.2.30, Anti-PARP-16, Anti-Poly [ADP-ribose] polymerase 16
• Código UNSPSC: 12352203
• NACRES: NA.41

Propriedades

• fonte biológica: rabbit
• conjugado: unconjugated
• forma do anticorpo: saturated ammonium sulfate (SAS) precipitated
• tipo de produto de anticorpo: primary antibodies
• clone: polyclonal
• forma: buffered aqueous solution
• reatividade de espécies: mouse, human
• técnica(s): indirect ELISA: 1:1000; western blot: 1:100-1:500
• nº de adesão NCBI: NP_803411
• nº de adesão UniProt: Q7TMM8
• Condições de expedição: dry ice
• temperatura de armazenamento: −20°C
• modificação pós-traducional do alvo: unmodified
• Informações sobre genes: human ... PARP16(214424)

Descrição

Descrição geral

Poly(ADP-ribosyl)ation is an immediate DNA-damage-dependent post-translational modification of histones and other nuclear proteins that contributes to the survival of injured proliferating cells. Poly(ADP-ribose) polymerases (PARPs) now constitute a large family of 18 proteins, encoded by different genes and displaying a conserved catalytic domain in which PARP-1 (113 kDa), the founding member, and PARP-2 (62 kDa) are so far the sole enzymes whose catalytic activity has been shown to be immediately stimulated by DNA strand breaks. A large repertoire of sequences encoding novel PARPs now extends considerably the field of poly(ADP-ribosyl)ation reactions to various aspects of the cell biology including cell proliferation and cell death. Some of these new members interact with each other, share common partners and common subcellular localizations suggesting possible fine tuning in the regulation of this post-translational modification of proteins.

Imunogênio

PARP16 (NP_803411, 221-258)
This antibody is generated from rabbits immunized with a KLH-conjugated synthetic peptide selected from the C-terminal region of mouse PARP16.

forma física

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.

Informações de segurança

• Código de classe de armazenamento: 10 - Combustible liquids
• Classe de risco de água (WGK): nwg
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable