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S7635

Sigma-Aldrich

Sulforhodamine 101

Dye content ~95 %, Powder

Sinônimo(s):

SR101; 2-(3-oxa-23-aza-9-azoniaheptacyclo[17.7.1.15,9.02,17.04,15.023,27.013,28]octacosa-1(27),2(17),4,9(28),13,15,18-heptaen-16-yl)-5-sulfobenzenesulfonate

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About This Item

Fórmula empírica (Notação de Hill):
C31H30N2O7S2
Número CAS:
60311-02-6
Peso molecular:
606.71
Beilstein:
3582548
Número CE:
262-159-4
Número MDL:
MFCD00012407
Código UNSPSC:
12171500
ID de substância PubChem:
24899749
NACRES:
NA.47

product name

Sulforhodamine 101, Dye content ~95 %

forma

powder

Nível de qualidade

100

composição

Dye content, ~95%

técnica(s)

microbe id | staining: suitable

cor

black
dark green to brown

solubilidade

methanol: 1 mg/mL

ε (coeficiente de extinção)

≥105000 at 573-579 nm in ethanol

fluorescência

λex 586 nm; λem 605 nm in H2O

aplicação(ões)

diagnostic assay manufacturing
hematology
histology

temperatura de armazenamento

room temp

cadeia de caracteres SMILES

OS(=O)(=O)c1ccc(C2=C3C=C4CCC[N+]5=C4C(CCC5)=C3Oc6c7CCCN8CCCc(cc26)c78)c(c1)S([O-])(=O)=O

InChI

1S/C31H30N2O7S2/c34-41(35,36)20-9-10-21(26(17-20)42(37,38)39)27-24-15-18-5-1-11-32-13-3-7-22(28(18)32)30(24)40-31-23-8-4-14-33-12-2-6-19(29(23)33)16-25(27)31/h9-10,15-17H,1-8,11-14H2,(H-,34,35,36,37,38,39)

chave InChI

COIVODZMVVUETJ-UHFFFAOYSA-N

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Descrição geral

Sulforhodamine 101 is a red fluorescent dye. It is water-soluble, amphoteric rhodamine.

Aplicação

Sulforhodamine 101 has been used:
  • to label astrocytes
  • in quantitative polymerase chain reaction (PCR)
  • to determine the degree of disintegration in tissue sample

Ações bioquímicas/fisiológicas

Sulforhodamine 101 can be specifically used as a marker of astroglia in the neocortex. It is commonly used for brain imaging. Studies suggest that sulforhodamine 101 may be used as an epileptogenic agent.

Código de classe de armazenamento

11 - Combustible Solids

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

Equipamento de proteção individual

Eyeshields, Gloves, type N95 (US)

Certificados de análise (COA)

Busque Certificados de análise (COA) digitando o Número do Lote do produto. Os números de lote e remessa podem ser encontrados no rótulo de um produto após a palavra “Lot” ou “Batch”.

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Nature neuroscience, 16(2), 219-226 (2013-01-08)
Neurons in primary sensory cortex have diverse response properties, whereas higher cortical areas are specialized. Specific connectivity may be important for areal specialization, particularly in the mouse, where neighboring neurons are functionally diverse. To examine whether higher visual areas receive
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Epilepsy is a group of neurological disorders commonly associated with the neuronal malfunction leading to generation of seizures. Recent reports point to a possible contribution of astrocytes into this pathology. We used the lithium-pilocarpine model of status epilepticus (SE) in
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