S3572

Stevioside hydrate

from Stevia sp., ≥98% (HPLC), powder, p-aminohippurate transepithelial transport inhibitor

• Sinônimo(s): (4α-13-[(2-O-β-D-Glucopyranosyl-β-D-glucopyranosyl)oxy]kaur-16-en-18-oic acid β-D-glucopyranosyl ester
• Fórmula empírica (Notação de Hill): C₃₈H₆₀O₁₈ · xH₂O
• Número CAS: 57817-89-7
• Peso molecular: 804.87 (anhydrous basis)
• Código UNSPSC: 12352200
• ID de substância PubChem: 329824534
• NACRES: NA.77

Propriedades

• product name: Stevioside hydrate, ≥98% (HPLC)
• fonte biológica: Stevia sp.
• Ensaio: ≥98% (HPLC)
• forma: powder
• cor: white
• solubilidade: DMSO: 25 mg/mL, clear
• temperatura de armazenamento: 2-8°C
• cadeia de caracteres SMILES: O.C[C@@]12CCC[C@](C)(C1CC[C@]34CC(=C)[C@](CCC23)(C4)O[C@@H]5O[C@H](CO)[C@@H](O)[C@H](O)[C@H]5O[C@@H]6O[C@H](CO)[C@@H](O)[C@H](O)[C@H]6O)C(=O)O[C@@H]7O[C@H](CO)[C@@H](O)[C@H](O)[C@H]7O
• InChI: 1S/C38H60O18.H2O/c1-16-11-37-9-5-20-35(2,7-4-8-36(20,3)34(50)55-32-29(49)26(46)23(43)18(13-40)52-32)21(37)6-10-38(16,15-37)56-33-30(27(47)24(44)19(14-41)53-33)54-31-28(48)25(45)22(42)17(12-39)51-31;/h17-33,39-49H,1,4-15H2,2-3H3;1H2/t17-,18-,19-,20+,21+,22-,23-,24-,25+,26+,27+,28-,29-,30-,31+,32+,33+,35-,36-,37-,38+;/m1./s1
• chave InChI: FVECWZKNZGXJJO-QMYNVHDOSA-N

Descrição

Aplicação

Stevioside hydrate has been used as a standard in high performance liquid chromatography (HPLC) for quantification of steviol glycosides.

Stevioside-induced ROS-mediated apoptosis was studied in human breast cancer cells.

Ações bioquímicas/fisiológicas

Stevioside hydrate is a diterpene glycoside present in Stevia sp.

Stevioside is a noncaloric natural sweetener, 300 times more potent than sucrose. It inhibits transepithelial transport of p-aminohippurate (PAH) by interfering with the organic anion transport system. At 0.5-1 mM, it showed no interaction with any organic anion transporters (OAT).

Stevioside reportedly has genotoxic effects in cultured mammalian cells.

Nota de preparo

Stevioside solutions should be prepared in DMSO. Highly pure stevioside has very poor water solubility.

Informações de segurança

• Código de classe de armazenamento: 11 - Combustible Solids
• Classe de risco de água (WGK): WGK 3
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable
• Equipamento de proteção individual: Eyeshields, Gloves