RES1052B-B7
Biotina
Fabricação farmacêutica
Sinônimo(s):
D-Biotina, Bios II, Coenzima R, Vitamina B7, Vitamina H
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About This Item
Fórmula empírica (Notação de Hill):
C10H16N2O3S
Número CAS:
Peso molecular:
244.31
Beilstein:
86838
Número CE:
Número MDL:
Código UNSPSC:
12352201
NACRES:
NA.21
Produtos recomendados
fonte biológica
synthetic
Nível de qualidade
Ensaio
97.5-100.5%
Formulário
powder
Impurezas
Trace metals; tested
cor
white
pf
231-233 °C (lit.)
adequação
suitable for manufacturing use
cadeia de caracteres SMILES
[H][C@]12CS[C@@H](CCCCC(O)=O)[C@@]1([H])NC(=O)N2
InChI
1S/C10H16N2O3S/c13-8(14)4-2-1-3-7-9-6(5-16-7)11-10(15)12-9/h6-7,9H,1-5H2,(H,13,14)(H2,11,12,15)/t6-,7-,9-/m0/s1
chave InChI
YBJHBAHKTGYVGT-ZKWXMUAHSA-N
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Descrição geral
Our SAFC® portfolio of high-quality raw materials for use in biopharmaceutical processing withstands strict quality control procedures plus the documentation and expertise to help our customers meet requirements as defined by the M-Clarity Program.
M-Clarity Program
Our comprehensive portfolio of upstream process chemicals not only provides biopharmaceutical manufacturers with high-quality raw materials for production of classical and novel therapies, but also helps them get to market faster and simplify regulatory challenges. Trust us to deliver supply chain transparency and reliable sourcing around the globe, streamlining your product qualification with best-in-class regulatory support and service.
M-Clarity Program
Our comprehensive portfolio of upstream process chemicals not only provides biopharmaceutical manufacturers with high-quality raw materials for production of classical and novel therapies, but also helps them get to market faster and simplify regulatory challenges. Trust us to deliver supply chain transparency and reliable sourcing around the globe, streamlining your product qualification with best-in-class regulatory support and service.
To request documentation for this product, please contact Customer Support and select ‘Product Documentation′. Please note that access to the documentation for this product requires a confidentiality disclosure agreement.
Embalagem
Product is available in the following package sizes:
RES1052B-B701X: 1 g container
RES1052B-B707X: 10 g container
RES1052B-B708X: 25 g container
RES1052B-B701X: 1 g container
RES1052B-B707X: 10 g container
RES1052B-B708X: 25 g container
Informações legais
SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany
Código de classe de armazenamento
11 - Combustible Solids
Classe de risco de água (WGK)
WGK 1
Ponto de fulgor (°F)
Not applicable
Ponto de fulgor (°C)
Not applicable
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Steven Lin et al.
Molecular bioSystems, 7(6), 1811-1821 (2011-03-26)
Biotin is an enzyme cofactor indispensable to metabolic fixation of carbon dioxide in all three domains of life. Although the catalytic and physiological roles of biotin have been well characterized, the biosynthesis of biotin remains to be fully elucidated. Studies
Carmen Smarandache-Wellmann et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 34(16), 5627-5639 (2014-04-18)
We describe synaptic connections through which information essential for encoding efference copies reaches two coordinating neurons in each of the microcircuits that controls limbs on abdominal segments of the crayfish, Pacifastacus leniusculus. In each microcircuit, these coordinating neurons fire bursts
Stéphane Mann et al.
Biochimica et biophysica acta, 1814(11), 1459-1466 (2010-12-25)
The four last steps of biotin biosynthesis, starting from pimeloyl-CoA, are conserved among all the biotin-producing microorganisms. Two enzymes of this pathway, the 8-amino-7-oxononanoate synthase (AONS) and the 7,8-diaminopelargonic acid aminotransferase (DAPA AT) are dependent on pyridoxal-5'-phosphate (PLP). This review
Majid Alfadhel et al.
Orphanet journal of rare diseases, 8, 83-83 (2013-06-08)
Biotin-responsive basal ganglia disease (BBGD) is an autosomal recessive neurometabolic disorder. It is characterized by sub acute encephalopathy with confusion, seizure, dysarthria and dystonia following a history of febrile illness. If left untreated with biotin, the disease can progress to
John E Cronan et al.
Current opinion in chemical biology, 15(3), 407-413 (2011-03-26)
Biotin synthesis requires the C7 α,ω-dicarboxylic acid, pimelic acid. Although pimelic acid was known to be primarily synthesized by a head to tail incorporation of acetate units, the synthetic mechanism was unknown. It has recently been demonstrated that in most
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