14400

Biotina

≥99.0% (T)

• Sinônimo(s): D-Biotina, Bios II, Coenzima R, Vitamina B7, Vitamina H
• Fórmula empírica (Notação de Hill): C₁₀H₁₆N₂O₃S
• Número CAS: 58-85-5
• Peso molecular: 244.31
• Beilstein: 86838
• Número CE: 200-399-3
• Número MDL: MFCD00005541
• Código UNSPSC: 12352201
• eCl@ss: 34058011
• ID de substância PubChem: 329750287
• NACRES: NA.21

Propriedades

• fonte biológica: synthetic
• Nível de qualidade: 200
• Ensaio: ≥99.0% (T)
• forma: powder
• atividade óptica: [α]20/D +91±2°, c = 1% in 0.1 M NaOH
• resíduo de ignição: ≤0.1% (as SO₄)
• perda: ≤0.5% loss on drying
• cor: colorless to white
• pf: 229-234 °C; 231-233 °C (lit.)
• solubilidade: alcohol: soluble 80mg/100 ml at 25 °C; water: soluble 22mg/100 ml at 25 °C; 0.1 M NaOH: 10 mg/mL at 25 °C, clear, colorless; H₂O: very soluble; organic solvents: insoluble
• traços de cátion: Ca: ≤50 mg/kg; Cd: ≤5 mg/kg; Co: ≤5 mg/kg; Cr: ≤5 mg/kg; Cu: ≤5 mg/kg; Fe: ≤10 mg/kg; K: ≤50 mg/kg; Mg: ≤5 mg/kg; Mn: ≤5 mg/kg; Na: ≤500 mg/kg; Ni: ≤5 mg/kg; Pb: ≤5 mg/kg; Zn: ≤5 mg/kg
• aplicação(ões): detection
• cadeia de caracteres SMILES: [H][C@]12CS[C@@H](CCCCC(O)=O)[C@@]1([H])NC(=O)N2
• InChI: 1S/C10H16N2O3S/c13-8(14)4-2-1-3-7-9-6(5-16-7)11-10(15)12-9/h6-7,9H,1-5H2,(H,13,14)(H2,11,12,15)/t6-,7-,9-/m0/s1
• chave InChI: YBJHBAHKTGYVGT-ZKWXMUAHSA-N

Descrição

Descrição geral

Biotin is readily available in several foods, like whole grains, nuts, legumes, unpolished rice and egg yolk. The normal gut flora also produces this vitamin.

Aplicação

Biotin has been used for testing the functionality of the Avidin-displaying phages. The product has also been used for labeling the swine anti-rabbit IgG antibody and peroxidase.

Ações bioquímicas/fisiológicas

Biotin acts as an important cofactor for carboxylase enzymes in various metabolic pathways. Biotin favors keratin synthesis and hence is used as a supplement for hair and nail growth. Deficiency of biotin shows several symptoms such as alopecia, conjunctivitis, seborrheic dermatitis, depression, lethargy, hypotonia and seizures.

Biotin also referred to as vitamin H or vitamin B7 is a water-soluble B-vitamin that induces two to three fold increase in guanylate cyclase activity in rat liver, kidney, colon, cerebellum, and heart. It also stimulates the sperm motility and prolongs the survival of cryopreserved human spermatozoa.

Outras notas

Reviews; Avidin-Biotin technology;

Informações de segurança

• Código de classe de armazenamento: 11 - Combustible Solids
• Classe de risco de água (WGK): WGK 1
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable
• Equipamento de proteção individual: Eyeshields, Gloves, type N95 (US)