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RAB0750

Sigma-Aldrich

Human PLAUR / Urokinase Plasminogen Activator Surface Receptor ELISA Kit

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About This Item

Código UNSPSC:
41116158
NACRES:
NA.32

reatividade de espécies

human

embalagem

kit of 96 wells (12 strips x 8 wells)

técnica(s)

ELISA: suitable

entrada

sample type cell culture supernatant(s)
sample type serum
sample type plasma

assay range

inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 15 pg/mL
standard curve range: 16.38-4000 pg/mL

método de detecção

colorimetric

Condições de expedição

wet ice

temperatura de armazenamento

−20°C

Informações sobre genes

human ... PLAUR(5329)

Categorias relacionadas

Descrição geral

The antibody pair provided in this kit recognizes human Urokinase Plasminogen Activator Surface Receptor.

Aplicação

For research use only. Not for use in diagnostic procedures.
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)

Ações bioquímicas/fisiológicas

Plasminogen activator, urokinase receptor (PLAUR) is implicated in tumor invasion, angiogenesis and metastasis. It acts as a key regulator of cell-surface plasminogen activator. It is involved in various normal and pathological processes. Overexpression of the gene has been observed in various types of cancers, including head and neck squamous cell carcinoma (HNSCC). Thus, it is considered as an potent biomarker for targeted imaging or therapy. Elevated expression of PLAUR leads to the progression of kidney disease in children.

Outras notas

A sample Certificate of Analysis is available for this product.
Please type the word sample in the text box provided for lot number.

Componentes do kit também disponíveis separadamente

Nº do produto
Descrição
SDS
  • RABTMB3ELISA Colorimetric TMB Reagent (HRP Substrate, Item H)SDS
  • RABSTOP3ELISA Stop Solution (Item I)SDS
  • RABWASH420X Wash Buffer (Item B)SDS

Pictogramas

Corrosion
GHS05

Palavra indicadora

Warning

Frases de perigo

H290

Declarações de precaução

P234 - P390

Classificações de perigo

Met. Corr. 1

Código de classe de armazenamento

8A - Combustible corrosive hazardous materials

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

Certificados de análise (COA)

Busque Certificados de análise (COA) digitando o Número do Lote do produto. Os números de lote e remessa podem ser encontrados no rótulo de um produto após a palavra “Lot” ou “Batch”.

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Visite a Biblioteca de Documentos

Fei Huang et al.
Mediators of inflammation, 2020, 7850179-7850179 (2020-04-24)
The soluble urokinase plasminogen activator receptor (suPAR) is associated with kidney diseases and is used as a prognostic factor of renal function progression. The aim of this study was to explore whether circulating suPAR was associated with antineutrophil cytoplasmic autoantibody-
Ümmügülsüm Can et al.
Journal of investigative medicine : the official publication of the American Federation for Clinical Research, 62(7), 938-943 (2014-08-16)
Chronic obstructive pulmonary disease (COPD) results from an abnormal inflammatory response of the lungs to noxious particles or gases. Serum soluble urokinase-type plasminogen activator receptor (suPAR) is a glycoprotein secreted during infections and inflammation. The main goal of this study
Association of Serum Soluble Urokinase Receptor Levels With Progression of Kidney Disease in Children.
Schaefer F, et al.
JAMA Pediatrics, 171(11), e172914-e172914 (2017)
Sven Wach et al.
Molecular therapy. Nucleic acids, 16, 272-283 (2019-04-02)
MIR143 is pathologically downregulated and may function as a tumor suppressor in prostate cancer. Likewise, the urokinase plasminogen activator receptor (UPAR) is overexpressed in prostate carcinoma, representing a negative prognostic marker and putative therapeutic target gene. In this paper, we
uPAR-targeted optical near-infrared (NIR) fluorescence imaging and PET for image-guided surgery in head and neck cancer: proof-of-concept in orthotopic xenograft model
Christensen A, et al.
Oncotarget, 8(9), 15407-15407 (2017)
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