RAB0361

Human MMP-1 ELISA Kit

for serum, plasma, cell culture supernatant and urine

• Sinônimo(s): MMP-1, Matrix metalloproteinase-1
• Código UNSPSC: 41116158
• NACRES: NA.32

Propriedades

• reatividade de espécies: human
• embalagem: kit of 96 wells (12 strips x 8 wells)
• técnica(s): ELISA: suitable; capture ELISA: suitable
• entrada: sample type plasma; sample type cell culture supernatant(s); sample type serum; sample type urine
• assay range: inter-assay cv: <12%; intra-assay cv: <10%; sensitivity: 8 pg/mL; standard curve range: 24.69-18000 pg/mL
• método de detecção: colorimetric
• Condições de expedição: wet ice
• temperatura de armazenamento: −20°C
• Informações sobre genes: human ... MMP1(4312)

Descrição

Descrição geral

The Human MMP-1 ELISA (Enzyme-Linked Immunosorbent Assay) kit is an in vitro enzyme-linked immunosorbent assay for the quantitative measurement of human MMP-1 pro and active forms in serum, plasma, cell culture supernatants and urine.

Imunogênio

Recombinant Human MMP1

Aplicação

For research use only. Not for use in diagnostic procedures.
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)
Human MMP-1 ELISA Kit has been used in ELISA assays.

Ações bioquímicas/fisiológicas

Matrix metalloproteinases (MMPs) enzymes play a central role in the maintenance and remodeling of the extracellular matrix. Elevated expression of their activity, caused either by up-regulation of their expression or down-regulation of their cognate inhibitors, has been implicated in various degenerative disorders, including arthritis, cardiovascular disease, skeletal growth-plate disorders, and cancer metastasis. MMP-1 is a secreted collagenase with specificity toward Type I, II, III, VII, and X collagens, aggrecan, serpins, and α2-macroglobulin. It is overexpressed in lumbar intervertebral disc degeneration (IDD). It might also be associated with osteoarthritis. MMP-1 is linked with juvenile idiopathic arthritis. Genetic variations in MMP-1 can affect the susceptibility and severity of this disease.

Outras notas

A sample Certificate of Analysis is available for this product.
Please type the word sample in the text box provided for lot number.

Componentes do kit também disponíveis separadamente

• RABELADE ELISA 5X Assay/Sample Diluent Buffer E (Item E2)
• RABSTOP3 ELISA Stop Solution (Item I)
• RABTMB3 ELISA Colorimetric TMB Reagent (HRP Substrate, Item H)
• RABWASH4 20X Wash Buffer (Item B)

Informações de segurança

• Pictogramas: GHS05
• Palavra indicadora: Warning
• Frases de perigo: H290
• Declarações de precaução: P234 - P390
• Classificações de perigo: Met. Corr. 1
• Código de classe de armazenamento: 8B - Non-combustible corrosive hazardous materials
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable