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RAB0325

Sigma-Aldrich

Inhibin-B EIA Kit

for serum, plasma, culture supernatant and cell lysates

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About This Item

Código UNSPSC:
41123300
NACRES:
NA.32

reatividade de espécies

rat, mouse, human

embalagem

kit of 96 wells (12 strips x 8 wells)

técnica(s)

ELISA: suitable
enzyme immunoassay: suitable

entrada

sample type plasma
sample type cell lysate
sample type serum
sample type culture supernatant(s)

assay range

inter-assay cv: <15%
intra-assay cv: <10%
sensitivity: 2 pg/mL
standard curve range: 1-10000 pg/mL

método de detecção

colorimetric

Condições de expedição

wet ice

temperatura de armazenamento

−20°C

Informações sobre genes

human ... INHBB(3625)

Descrição geral

Inhibin-B (INHBB) is a heterodimeric glycoprotein with disulfide-linkage. It is produced by granulosa cells in the ovary. The INHBB gene is mapped to human chromosome 2q14.2. Inhibin-B inhibits follicle-stimulating hormone (FSH) secretion and synthesis. It may serve in diagnosing testicular function and as an indicator of Sertoli cell numbers and function. Inhibin B may serve as a marker for spermatogenesis.
The Inhibin B Enzyme Immunoassay (EIA) Kit is an in vitro quantitative assay for detecting Inhibin B peptide based on the principle of Competitive Enzyme Immunoassay. EIA-INB-1 targets the β B subunit, and therefore theoretically detects Activin B and Activin AB in addition to Inhibin B.

Imunogênio

Inhibin-B, synthetic peptide

Aplicação

Inhibin-B EIA Kit has been used in quantification of Inhibin-B using enzyme-linked immunosorbent assay (ELISA) in Zika virus-infected human Sertoli cells (HSerC) and 8-week-old mice.

Componentes do kit também disponíveis separadamente

Nº do produto
Descrição
SDS

Pictogramas

Corrosion
GHS05

Palavra indicadora

Warning

Frases de perigo

H290

Declarações de precaução

P234 - P390

Classificações de perigo

Met. Corr. 1

Código de classe de armazenamento

8A - Combustible corrosive hazardous materials

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Certificados de análise (COA)

Lot/Batch Number

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S J Meachem et al.
European journal of endocrinology, 145(5), 561-571 (2001-11-27)
The recent availability of specific inhibin assays has demonstrated that inhibin B is the relevant circulating inhibin form in the human male. Inhibin B is a dimer of an alpha and a betaB subunit. It is produced exclusively by the
Mahamud-Ur Rashid et al.
PLoS neglected tropical diseases, 14(6), e0008335-e0008335 (2020-06-09)
Zika virus (ZIKV), a neglected tropical disease until its re-emergence in 2007, causes microcephaly in infants and Guillain-Barré syndrome in adults. Its re-emergence and spread to more than 80 countries led the World Health Organization in 2016 to declare a
R Mayor et al.
British journal of cancer, 100(10), 1534-1539 (2009-04-23)
Large chromosomal regions can be suppressed in cancer cells as denoted by hypermethylation of neighbouring CpG islands and downregulation of most genes within the region. We have analysed the extent and prevalence of long-range epigenetic silencing at 2q14.2 (the first
Liang-Yu Chen et al.
Proceedings of the National Academy of Sciences of the United States of America, 113(7), 1829-1834 (2016-02-03)
Spermatogonial stem cells (SSCs) are a subpopulation of undifferentiated spermatogonia located in a niche at the base of the seminiferous epithelium delimited by Sertoli cells and peritubular myoid (PM) cells. SSCs self-renew or differentiate into spermatogonia that proliferate to give

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