RAB0235
Human IGFBP-3 ELISA Kit
for serum, plasma, cell culture supernatant and urine
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About This Item
Código UNSPSC:
41116158
NACRES:
NA.32
Produtos recomendados
reatividade de espécies
human
embalagem
kit of 96 wells (12 strips x 8 wells)
técnica(s)
ELISA: suitable
capture ELISA: suitable
entrada
sample type plasma
sample type serum
sample type cell culture supernatant(s)
sample type urine
assay range
inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 80 pg/mL
standard curve range: 74.07-18000 pg/mL
método de detecção
colorimetric
Condições de expedição
wet ice
temperatura de armazenamento
−20°C
Informações sobre genes
human ... IGFBP3(3486)
Categorias relacionadas
Descrição geral
The Human IGFBP-3 ELISA (Enzyme-Linked mmunosorbent Assay) kit is an in vitro enzyme-linked immunosorbent assay for the quantitative measurement of human IGFBP-3 in serum, plasma, cell culture supernatants and urine.
Imunogênio
Recombinant Human IGFBP3
Aplicação
For research use only. Not for use in diagnostic procedures.
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)
Ações bioquímicas/fisiológicas
Insulin-like growth factor-binding protein 3 (IGFBP3) is implicated in cell survival. In addition, it also facilitates cell death and tumorigenesis. Epigenetic changes in IGFBP3 affect non-small-cell lung cancer, hepatocellular carcinoma, ovarian cancer, skin cancer, urological cancers, breast cancer and gastric cancer. IGFBP3 is a primary growth inhibitor and can reverse the mitogenic functions of IGF-1 (insulin like growth factor 1) by inducing apoptosis.
Outras notas
A sample Certificate of Analysis is available for this product.
Please type the word sample in the text box provided for lot number.
Please type the word sample in the text box provided for lot number.
Componentes do kit também disponíveis separadamente
Nº do produto
Descrição
SDS
Palavra indicadora
Warning
Frases de perigo
Declarações de precaução
Classificações de perigo
Met. Corr. 1
Código de classe de armazenamento
8A - Combustible corrosive hazardous materials
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The low IGFBP-3 level is associated with esophageal cancer patients: a meta-analysis.
Song G, et al.
World Journal of Surgical Oncology, 14(1), 307-307 (2016)
Insulin-like growth factor binding protein-3 mediates interleukin-24-induced apoptosis through inhibition of the mTOR pathway in prostate cancer.
Du Y, et al.
Oncology, 34(5), 2273-2281 (2015)
Evaluation of Insulin-like Growth Factor-1 and Insulin-like Growth Factor Binding Protein-3 Expression Levels in Patients with Chronic Lymphocytic Leukemia.
Ayer M, et al.
Turkish journal of haematology : official journal of Turkish Society of Haematology, 33(4), 335-335 (2016)
Yan Wang et al.
Medical oncology (Northwood, London, England), 31(5), 921-921 (2014-03-29)
Growth factors in the brain are important to depression. We investigated the relationship between serum insulin-like growth factor (IGF-1) and IGF-binding protein-3 (IGFBP-3) concentration and risk of depression and the effect of psychological intervention on outcomes of high-grade glioma patients
Francesca D'Addio et al.
Nature communications, 13(1), 684-684 (2022-02-05)
Loss of pancreatic beta cells is a central feature of type 1 (T1D) and type 2 (T2D) diabetes, but a therapeutic strategy to preserve beta cell mass remains to be established. Here we show that the death receptor TMEM219 is
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