IGFBP3
insulin-like growth factor binding protein 3
Synonyms:
BP-53, IBP3
Species:
Human IGFBP3 (3486), Mouse Igfbp3 (16009), Rat Igfbp3 (24484), Zebrafish igfbp3 (403079), chicken IGFBP3 (420790), dog IGFBP3 (491618), domestic cat IGFBP3 (101080442), cow IGFBP3 (282261), sheep IGFBP3 (100286737), domestic guinea pig Igfbp3 (100714097)
UniProtKB ID:
Gene ID:
- Human(3486) Summary: This gene is a member of the insulin-like growth factor binding protein (IGFBP) family and encodes a protein with an IGFBP domain and a thyroglobulin type-I domain. The protein forms a ternary complex with insulin-like growth factor acid-labile subunit (IGFALS) and either insulin-like growth factor (IGF) I or II. In this form, it circulates in the plasma, prolonging the half-life of IGFs and altering their interaction with cell surface receptors. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]
- Mouse(16009) insulin-like growth factor binding protein 3
- Rat(24484) insulin-like growth factor binding protein 3
- Zebrafish(403079) insulin-like growth factor binding protein 3
- chicken(420790) insulin-like growth factor binding protein 3
- dog(491618) insulin-like growth factor binding protein 3
- domestic cat(101080442) insulin-like growth factor binding protein 3
- cow(282261) insulin-like growth factor binding protein 3
- sheep(100286737) insulin-like growth factor binding protein 3
- domestic guinea pig(100714097) insulin-like growth factor binding protein 3
- naked mole-rat(101710997) insulin-like growth factor binding protein 3
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