R6527

Reboxetine mesylate hydrate

>96% (HPLC), solid

• Sinônimo(s): (2R)-rel-2-[(R)-(2-Ethoxyphenoxy)phenylmethyl]morpholine, Edronax, Vestra
• Fórmula empírica (Notação de Hill): C₁₉H₂₃NO₃ · CH₃SO₃H · xH₂O
• Número CAS: 98769-84-7
• Peso molecular: 409.50 (anhydrous basis)
• Número MDL: MFCD11046031
• Código UNSPSC: 12352200
• ID de substância PubChem: 24724592
• NACRES: NA.77

Propriedades

• Nível de qualidade: 100
• Ensaio: >96% (HPLC)
• forma: solid
• condição de armazenamento: desiccated
• cor: white to tan
• solubilidade: H₂O: >5 mg/mL at ≤60 °C
• Condições de expedição: wet ice
• temperatura de armazenamento: 2-8°C
• cadeia de caracteres SMILES: O.CS(O)(=O)=O.CCOc1ccccc1O[C@@H]([C@H]2CNCCO2)c3ccccc3
• InChI: 1S/C19H23NO3.CH4O3S.H2O/c1-2-21-16-10-6-7-11-17(16)23-19(15-8-4-3-5-9-15)18-14-20-12-13-22-18;1-5(2,3)4;/h3-11,18-20H,2,12-14H2,1H3;1H3,(H,2,3,4);1H2/t18-,19-;;/m1../s1
• chave InChI: SZPHEVAYLIVGRC-BAMQSBMESA-N

Descrição

Aplicação

Reboxetine mesylate hydrate has been used as a selective norepinephrine transport blocker:

• to study its effects on the surge of dopamine in the cortex of mice brain
• to study its anti-immobility effects on the behavior of mice
• to analyze its effects on the probabilistic reversal learning task in rodents

Ações bioquímicas/fisiológicas

Reboxetine exhibits anti-depressant activity.

Reboxetine mesylate hydrate is a selective noradrenaline uptake inhibitor.

Características e benefícios

This compound is featured on the Biogenic Amine Transporters page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Informações de segurança

• Código de classe de armazenamento: 11 - Combustible Solids
• Classe de risco de água (WGK): WGK 3
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable
• Equipamento de proteção individual: Eyeshields, Gloves, type N95 (US)