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R1908

Sigma-Aldrich

Remifentanil hydrochloride

≥97% (HPLC), powder

Sinônimo(s):

3-[methoxycarbonyl-4-[(1-oxopropyl)phenylamino]1-piperidine]propanoic acid methyl ester hydrochloride, GI-87084B, Remifentanyl, Ultiva

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About This Item

Fórmula empírica (Notação de Hill):
C20H28N2O5·HCl
Número CAS:
132539-07-2
Peso molecular:
412.91
Número MDL:
MFCD00910882
Código UNSPSC:
12352200
ID de substância PubChem:
329824010

Nível de qualidade

100

Ensaio

≥97% (HPLC)

forma

powder

controle de medicamentos

USDEA Schedule II; regulated under CDSA - not available from Sigma-Aldrich Canada; estupefaciente (Spain); Decreto Lei 15/93: Tabela IA (Portugal)

condição de armazenamento

desiccated

cor

white to off-white

solubilidade

H2O: ≥20 mg/mL

temperatura de armazenamento

2-8°C

cadeia de caracteres SMILES

O=C(CC)N(C1(CCN(CCC(OC)=O)CC1)C(OC)=O)C2=CC=CC=C2.[H]Cl

InChI

1S/C20H28N2O5.ClH/c1-4-17(23)22(16-8-6-5-7-9-16)20(19(25)27-3)11-14-21(15-12-20)13-10-18(24)26-2;/h5-9H,4,10-15H2,1-3H3;1H

chave InChI

WFBMIPUMYUHANP-UHFFFAOYSA-N

Informações sobre genes

human ... OPRM1(4988)

Procurando produtos similares? Visita Guia de comparação de produtos

Ações bioquímicas/fisiológicas

Remifentanil hydrochloride is a mu opioid receptor agonist, anesthetic, and analgesic compound. Remifentanil was developed as an ultra-short-acting mu opioid receptor agonist with improved pharmacodynamic properties.

Características e benefícios

This compound is featured on the Opioid Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Pictogramas

Health hazard
GHS08

Palavra indicadora

Warning

Frases de perigo

H371

Classificações de perigo

STOT SE 2

Órgãos-alvo

Respiratory system

Código de classe de armazenamento

11 - Combustible Solids

Classe de risco de água (WGK)

WGK 1

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

Certificados de análise (COA)

Busque Certificados de análise (COA) digitando o Número do Lote do produto. Os números de lote e remessa podem ser encontrados no rótulo de um produto após a palavra “Lot” ou “Batch”.

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Visite a Biblioteca de Documentos

Anthony G Doufas et al.
PloS one, 8(1), e54807-e54807 (2013-02-06)
Obstructive sleep apnea (OSA) is characterized by recurrent nocturnal hypoxia and sleep disruption. Sleep fragmentation caused hyperalgesia in volunteers, while nocturnal hypoxemia enhanced morphine analgesic potency in children with OSA. This evidence directly relates to surgical OSA patients who are
Clément Marcelin et al.
Journal of vascular and interventional radiology : JVIR, 29(7), 975-980 (2018-05-08)
To evaluate the safety and efficacy of endovascular management of pulmonary artery lesions caused by lung tumors. Nineteen patients (15 men, 4 women; average age: 60.3 years, range, 51-86 years) treated for massive or recurrent hemoptysis with transarterial pulmonary artery
N A Pedersen et al.
Acta anaesthesiologica Scandinavica, 57(8), 988-995 (2013-07-10)
Magnetic resonance imaging (MRI) of children is generally performed under sedation or with general anaesthesia (GA), but the ideal regimen has not been found. The aim of this study was to see if propofol-remifentanil would be a suitable alternative for
Arne Kristian Skulberg et al.
European journal of clinical pharmacology, 74(7), 873-883 (2018-03-24)
This study aimed to develop a model for pharmacodynamic and pharmacokinetic studies of naloxone antagonism under steady-state opioid agonism and to compare a high-concentration/low-volume intranasal naloxone formulation 8 mg/ml to intramuscular 0.8 mg. Two-way crossover in 12 healthy volunteers receiving naloxone while
T M Hemmerling et al.
British journal of anaesthesia, 110(6), 1031-1039 (2013-02-22)
We have developed an automatic anaesthesia system for closed-loop administration of anaesthesia drugs. The control variables used were bispectral index (BIS) and Analgoscore for hypnosis and antinociception, respectively. One hundred and eighty-six patients were randomly enrolled in two groups. Propofol
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