PZ0129

CP-380736

≥98% (HPLC)

• Sinônimo(s): 6,7-Bis(2-methoxyethoxy)-3,4-dihydroquinazolin-4-one, 6,7-Bis(2-methoxyethoxy)-4(3H)-quinazolinone, PF-00520893
• Fórmula empírica (Notação de Hill): C₁₄H₁₈N₂O₅
• Número CAS: 179688-29-0
• Peso molecular: 294.30
• Número MDL: MFCD02678087
• Código UNSPSC: 51111800
• ID de substância PubChem: 329823716
• NACRES: NA.77

Propriedades

• Nível de qualidade: 100
• Ensaio: ≥98% (HPLC)
• forma: powder
• cor: off-white to light tan
• solubilidade: DMSO: ≥10 mg/mL
• temperatura de armazenamento: room temp
• cadeia de caracteres SMILES: COCCOc1cc2N=CNC(=O)c2cc1OCCOC
• InChI: 1S/C14H18N2O5/c1-18-3-5-20-12-7-10-11(15-9-16-14(10)17)8-13(12)21-6-4-19-2/h7-9H,3-6H2,1-2H3,(H,15,16,17)
• chave InChI: PMQWTUWLIGJTQD-UHFFFAOYSA-N

Descrição

Ações bioquímicas/fisiológicas

CP-380736 is an inhibitor of the epidermal growth factor receptor (EGFR). EGFR is a tyrosine kinase that activates MAPK, JNK, and Akt pathways, and is an important mediator of several types of cancer, including lung cancer and glioblastoma multiforme.

Características e benefícios

This compound is a featured product for Kinase Phosphatase Biology research. Click here to discover more featured Kinase Phosphatase Biology products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

Informações de segurança

• Código de classe de armazenamento: 11 - Combustible Solids
• Classe de risco de água (WGK): WGK 3
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable