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PVP1

Sigma-Aldrich

Poly(vinylpyrrolidone)–Iodine complex

Sinônimo(s):

PVP-Iodine, Polyvinylpyrrolidone Iodine, PVP-I, Povadyne® antiseptic

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About This Item

Número CAS:
25655-41-8
Número MDL:
MFCD00084483
Código UNSPSC:
51102829
ID de substância PubChem:
24899316
NACRES:
NA.85

Formulário

powder

solubilidade

H2O: 100 mg/mL

espectro de atividade do antibiótico

Gram-negative bacteria
Gram-positive bacteria
fungi
parasites
viruses
yeast

Modo de ação

protein synthesis | interferes

cadeia de caracteres SMILES

II.C=CN1CCCC1=O

InChI

1S/C6H9NO.I2/c1-2-7-5-3-4-6(7)8;1-2/h2H,1,3-5H2;

chave InChI

CPKVUHPKYQGHMW-UHFFFAOYSA-N

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Aplicação

Poly(vinylpyrrolidone)–Iodine complex, or PVP-I, has been used to study microbial decontamination of human donor eyes and the inactivation of infectious hematopoietic necrosis virus.

Ações bioquímicas/fisiológicas

PVP-1 is used as a slow iodine release formulation that iodinates lipids and oxidizes cell compounds such as tyrosine sidechains. It is used as a carbon nanotube coating agent to improve water solubility.

Outras notas

An iodophor; "tamed iodine."
Keep container tightly closed in a dry and well-ventilated place.

Informações legais

Povadyne is a registered trademark of National Patent Development Corp.

Pictogramas

CorrosionEnvironment
GHS05,GHS09

Palavra indicadora

Danger

Frases de perigo

H315,H318,H411

Classificações de perigo

Aquatic Chronic 2 - Eye Dam. 1 - Skin Irrit. 2

Código de classe de armazenamento

11 - Combustible Solids

Classe de risco de água (WGK)

WGK 2

Ponto de fulgor (°F)

>212.0 °F - Not applicable

Ponto de fulgor (°C)

> 100 °C - Not applicable

Equipamento de proteção individual

Eyeshields, Gloves, type N95 (US)

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Certificados de análise (COA)

Lot/Batch Number
SLCJ4659
SLCF2875
SLBX1906
SLBW1862
SLBM1060V

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X X Hao et al.
Poultry science, 92(10), 2560-2566 (2013-09-21)
Lots of microorganisms exist in layer houses can cause bird diseases and worker health concerns. Spraying chemical disinfectants is an effective way to decontaminate pathogenic microorganisms in the air and on surfaces in poultry houses. Slightly acidic electrolyzed water (SAEW
Michael P Labare et al.
American journal of infection control, 41(4), 360-361 (2012-10-30)
Two commonly used disinfectants, a quaternary ammonium salt and povidone-iodine, were tested for effectiveness against unembryonated Ascaris suum eggs. The quaternary ammonium salt (alkyl dimethyl benzyl ammonium chloride) had no effect on the Ascaris eggs (10 minutes and 22°C) when
Jo C Dumville et al.
The Cochrane database of systematic reviews, 3(3), CD003949-CD003949 (2013-04-02)
Surgical site infection rates in the month following clean surgery vary from 0.6% (knee prosthesis) to 5% (limb amputation). Due to the large number of clean surgical procedures conducted annually the costs of these surgical site infections (SSIs) can be
Karen Pawlowski et al.
Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology, 34(1), 167-174 (2012-12-04)
Repeated applications of low-concentration povidone iodine (PI) combined with dexamethasone (Dex) through a tympanic membrane ventilation tube will not cause ototoxic changes in the rat. Otitis externa (OE) and acute otitis media (AOM) are 2 of the most common otologic
Yangzi Jiang et al.
Acta biomaterialia, 9(9), 8089-8098 (2013-05-28)
Polyvinylpyrrolidone-iodine (Povidone-iodine, PVP-I) is widely used as an antiseptic agent for lavation during joint surgery; however, the biological effects of PVP-I on cells from joint tissue are unknown. This study examined the biocompatibility and biological effects of PVP-I on cells
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