PHG0005
BIS-TRIS propano
Fabricação farmacêutica
Sinônimo(s):
1,3-Bis [tris (hidroximetil) metilamino] propano
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About This Item
Fórmula linear:
CH2[CH2NHC(CH2OH)3]2
Número CAS:
Peso molecular:
282.33
Beilstein:
1786109
Número CE:
Número MDL:
Código UNSPSC:
12161705
NACRES:
NA.21
Produtos recomendados
fonte biológica
synthetic
Nível de qualidade
Formulário
powder
técnica(s)
cell culture | mammalian: suitable
Impurezas
Endotoxin, microbial, and trace metals; tested
faixa de pH útil
6.3-9.5
pKa (25 °C)
(1) 6.8, (2) 9.0
pf
164-165 °C (lit.)
adequação
suitable for manufacturing use
atividade externa
Cytotoxicity, DNase, NICKase, RNase, and Protease; tested
cadeia de caracteres SMILES
OCC(CO)(CO)NCCCNC(CO)(CO)CO
InChI
1S/C11H26N2O6/c14-4-10(5-15,6-16)12-2-1-3-13-11(7-17,8-18)9-19/h12-19H,1-9H2
chave InChI
HHKZCCWKTZRCCL-UHFFFAOYSA-N
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Descrição geral
Our SAFC® portfolio of high-quality raw materials for use in biopharmaceutical processing withstands strict quality control procedures plus the documentation and expertise to help our customers meet requirements as defined by the M-Clarity Program.
M-Clarity Program
Buffer quality is vital for the success of biopharmaceutical processes, because buffers are indispensable in nearly every production step.
Our broad portfolio of buffer materials manufactured under appropriate controls is tailored to your needs. Ranging from non-GMP grades for low-risk application, to IPEC-PQG GMP for higher-risk applications, we have products covering all your manufacturing needs.
M-Clarity Program
Buffer quality is vital for the success of biopharmaceutical processes, because buffers are indispensable in nearly every production step.
Our broad portfolio of buffer materials manufactured under appropriate controls is tailored to your needs. Ranging from non-GMP grades for low-risk application, to IPEC-PQG GMP for higher-risk applications, we have products covering all your manufacturing needs.
Aplicação
Bis Tris Propane is a unique biological buffer also referred to as a “Universal” buffer, which means the buffer capacity covers a wide range. Bis Tris Propane has two pKas of 6.3 and 9.5, which expands the buffering range from 5.0-10.5-making this a versatile buffer for biological systems. Bis Tris Propane is considered to be non-toxic to culture cell lines and provides high-solution clarity.
A review of DNA polymerase techniques lists bis tris propane as a suitable buffer for PCR methods as a universal buffer pH gradient is employed.
A review of DNA polymerase techniques lists bis tris propane as a suitable buffer for PCR methods as a universal buffer pH gradient is employed.
Informações legais
SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany
substituído por
Nº do produto
Descrição
Preços
Código de classe de armazenamento
11 - Combustible Solids
Classe de risco de água (WGK)
WGK 3
Ponto de fulgor (°F)
Not applicable
Ponto de fulgor (°C)
Not applicable
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