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P3418

Sigma-Aldrich

Poly-(α,β)-DL-aspartic acid sodium salt

mol wt 2,000-11,000

Sinônimo(s):

Aspartic acid homopolymer sodium salt

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About This Item

Número CAS:
94525-01-6
Número MDL:
MFCD00166658
Código UNSPSC:
12352209
NACRES:
NA.26

forma

powder

peso molecular

2,000-11,000

cor

white to off-white

temperatura de armazenamento

−20°C

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Aplicação


  • Improving the effectiveness of (-)-epigallocatechin gallate (EGCG) against rabbit atherosclerosis by EGCG-loaded nanoparticles prepared from chitosan and polyaspartic acid.: This research highlights the development of nanoparticles using polyaspartic acid to enhance the bioavailability and therapeutic effect of EGCG in treating atherosclerosis (Hong et al., 2014).

  • Polyaspartate, a biodegradable chelant that improves the phytoremediation potential of poplar in a highly metal-contaminated agricultural soil.: The study evaluates the use of polyaspartate in enhancing the phytoremediation capabilities of poplar trees, showcasing its environmental application for soil decontamination (Lingua et al., 2014).

  • Modulation of calcium oxalate dihydrate growth by selective crystal-face binding of phosphorylated osteopontin and polyaspartate peptide showing occlusion by sectoral (compositional) zoning.: This research investigates the role of polyaspartate in modulating the growth of calcium oxalate crystals, with implications for understanding kidney stone formation (Chien et al., 2009).

Nota de preparo

Prepared by thermal polycondensation.

Nota de análise

Molecular weight based on viscosity.

Outras notas

For additional technical information on polyamino acids please visit the Polyamino acid FAQ resource.

Código de classe de armazenamento

11 - Combustible Solids

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

Certificados de análise (COA)

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Yangzhi Guping et al.
Drug delivery, 12(2), 89-96 (2005-04-15)
A new class of biodegradable poly-amino acid, alpha,beta-poly[(N-hydroxypropyl/aminoethyl)-DL-Aspartamide-co-L-Lysine] (PHAAL), was synthesized by ring-opening of poly[succinimide-co-lysine](PSL) with n-propanolamine and ethylene diamine after thermal copolycondensation of DL-Aspartic acid and L-lysine under reduced pressure. Different ratio feeds of PSL were obtained and characterized
Lin Gui et al.
Nanomedicine (London, England), 5(5), 703-714 (2010-07-29)
Applying nanoscale assembly to the design of a thrombolytic agent. poly-alpha,beta-DL-aspartyl-L-alanine (molecular weight: 15726 atomic mass units) from the thermal polycondensation of DL-aspartic acid and the amidation of polysuccimide with L-alanine. The correlation of concentration and pH with nanofeatures, the
Fabio Nudelman et al.
Nanoscale, 2(11), 2436-2439 (2010-09-14)
Amorphous calcium carbonate (ACC) nanoparticles of different size are prepared using a flow system. Post-synthesis stabilization with a layer of poly[(α,β)-dl-aspartic acid] leads to stabilization of the ACC, but only for particles <100 nm. Larger and uncoated particles readily convert
Kovacs, J.
The Journal of Organic Chemistry, 26, 1084-1084 (1961)

Artigos

Poly(Amino Acid) Block Copolymers for Drug Delivery and other Biomedical Applications

Humankind has utilized protein materials throughout its existence, starting with the use of materials such as wool and silk for warmth and protection from the elements and continuing with the use of recombinant DNA techniques to synthesize proteins with unique and useful properties.

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