N4267

Neurokinin A

≥97% (HPLC)

• Sinônimo(s): α-Neurokinin, Neuromedin L, Substance K
• Fórmula linear: C₅₀H₇₉N₁₃O₁₅S
• Número CAS: 86933-74-6
• Peso molecular: 1133.32
• Número MDL: MFCD00167560
• Código UNSPSC: 51111800
• ID de substância PubChem: 24897700
• NACRES: NA.32

Propriedades

• Nível de qualidade: 200
• Ensaio: ≥97% (HPLC)
• forma: powder
• composição: Peptide content, ≥70%
• nº de adesão UniProt: P20366
• temperatura de armazenamento: −20°C
• cadeia de caracteres SMILES: CSCCC(NC(=O)C(CC(C)C)NC(=O)CNC(=O)C(NC(=O)C(Cc1ccccc1)NC(=O)C(CO)NC(=O)C(CC(O)=O)NC(=O)C(NC(=O)C(CCCCN)NC(=O)C(N)Cc2cnc[nH]2)C(C)O)C(C)C)C(N)=O
• InChI: 1S/C50H80N14O14S/c1-26(2)18-34(45(73)58-32(42(53)70)15-17-79-6)57-38(67)23-55-49(77)40(27(3)4)63-47(75)35(19-29-12-8-7-9-13-29)60-48(76)37(24-65)62-46(74)36(21-39(68)69)61-50(78)41(28(5)66)64-44(72)33(14-10-11-16-51)59-43(71)31(52)20-30-22-54-25-56-30/h7-9,12-13,22,25-28,31-37,40-41,65-66H,10-11,14-21,23-24,51-52H2,1-6H3,(H2,53,70)(H,54,56)(H,55,77)(H,57,67)(H,58,73)(H,59,71)(H,60,76)(H,61,78)(H,62,74)(H,63,75)(H,64,72)(H,68,69)
• chave InChI: HEAUFJZALFKPBA-UHFFFAOYSA-N
• Informações sobre genes: human ... TAC1(6863)

Descrição

Amino Acid Sequence

His-Lys-Thr-Asp-Ser-Phe-Val-Gly-Leu-Met-NH2

Descrição geral

Neurokinin A is an 11 amino acid peptide. It is a member of tachykinin family, which includes neurokinin A, neurokinin B, neuropeptide K, neuropeptide Y and hemokinin-1. The gene encoding neurokinin A is localized on human chromosome 7q21.3.

Ações bioquímicas/fisiológicas

Neurokinin A improves the multiplication and paracrine ability of stem cells acquired from adipose in vitro. It participates in the movement of several organ tracts, triggers glandular secretion and controls autonomic reflexes. Neurokinin A plays an important role in neuroimmune and systemic autoimmune/inflammatory conditions like multiple sclerosis (MS), rheumatoid arthritis, inflammatory bowel disease and also in infections and cancer.

Outras notas

Lyophilized from 0.1% TFA in H2O

Informações de segurança

• Código de classe de armazenamento: 11 - Combustible Solids
• Classe de risco de água (WGK): WGK 3
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable
• Equipamento de proteção individual: Eyeshields, Gloves, type N95 (US)