N0287

NNC 55-0396 hydrate

≥98% (HPLC)

• Sinônimo(s): (1S,2S)-2-(2-(N-[(3-Benzimidazol-2-yl)propyl]-N-methylamino)ethyl)-6-fluoro-1,2,3,4-tetrahydro-1-isopropyl-2-naphtyl cyclopropanecarboxylate dihydrochloride hydrate, NNC55-0396
• Fórmula empírica (Notação de Hill): C₃₀H₄₀Cl₂FN₃O₂ · xH₂O
• Peso molecular: 564.56 (anhydrous basis)
• Número MDL: MFCD12910446
• Código UNSPSC: 12352200
• ID de substância PubChem: 24278523
• NACRES: NA.77

Propriedades

• Ensaio: ≥98% (HPLC)
• forma: solid
• condição de armazenamento: desiccated
• cor: white
• solubilidade: H₂O: >10 mg/mL
• originador: Roche
• temperatura de armazenamento: 2-8°C
• cadeia de caracteres SMILES: O.Cl.Cl.CC(C)[C@H]1c2ccc(F)cc2CC[C@@]1(CCN(C)CCCc3nc4ccccc4[nH]3)OC(=O)C5CC5
• InChI: 1S/C30H38FN3O2.2ClH.H2O/c1-20(2)28-24-13-12-23(31)19-22(24)14-15-30(28,36-29(35)21-10-11-21)16-18-34(3)17-6-9-27-32-25-7-4-5-8-26(25)33-27;;;/h4-5,7-8,12-13,19-21,28H,6,9-11,14-18H2,1-3H3,(H,32,33);2*1H;1H2/t28-,30-;;;/m0.../s1
• chave InChI: ICVIUVXDXJUZRQ-SHQDEPIZSA-N

Descrição

Ações bioquímicas/fisiológicas

NNC-55-0396 is a T-type calcium channel antagonists. It is the structural analog of mibefradil. NNC-55-0396 has the ability to block cell proliferation and stimulate cell apoptosis in leukemia cell lines.

Selective T-type calcium channel inhibitor

Características e benefícios

This compound was developed by Roche. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Informações de segurança

• Código de classe de armazenamento: 11 - Combustible Solids
• Classe de risco de água (WGK): WGK 3
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable
• Equipamento de proteção individual: Eyeshields, Gloves, type N95 (US)