MAK491

Formate Assay Kit

sufficient for 100 colorimetric tests

• Sinônimo(s): Formate Test Kit
• Código UNSPSC: 12161503
• NACRES: NA.84

Propriedades

• Nível de qualidade: 100
• aplicação(ões): environmental
• método de detecção: colorimetric
• doença(s) relevante(s): neurological disorders
• Condições de expedição: wet ice
• temperatura de armazenamento: −20°C

Descrição

Descrição geral

Formate is the anion derived from formic acid, the simplest carboxylic acid. It is also the metabolic byproduct of formaldehyde metabolism in the body, and the eventual metabolic byproduct of methanol, which is first broken down to formaldehyde. At high levels, formate is neurotoxic to the central nervous system and can cause blindness, coma, and death. Although naturally present in the body at low levels, elevated levels of formate may be used as an indicator of formaldehyde exposure and methanol poisoning.

Características e benefícios

• Linear detection range 0.050 to 5 mM formate.
• Compatible with high-throughput handling systems.

Adequação

The kit is suitable for the determination of formate in biological samples such as urine and serum.

Princípio

The Formate Assay Kit is based on the formate dehydrogenase catalyzed oxidation of formate, which generates carbon dioxide and NADH that reduces a formazan (MTT) dye. The intensity of the reduced MTT, measured at 565 nm, is directly proportional to the formate concentration in the sample.

Informações de segurança

• Código de classe de armazenamento: 10 - Combustible liquids
• Classe de risco de água (WGK): WGK 2