MAK068
MPO Colorimetric Activity Assay Kit
sufficient for 100 colorimetric tests
Sinônimo(s):
Myeloperoxidase Colorimetric Activity Assay Kit
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About This Item
Código UNSPSC:
12161503
NACRES:
NA.84
Produtos recomendados
uso
sufficient for 100 colorimetric tests
método de detecção
colorimetric
doença(s) relevante(s)
cancer; cardiovascular diseases; hematological disorder
temperatura de armazenamento
−20°C
Informações sobre genes
human ... MPO(4353)
mouse ... MPO(17523)
rat ... MPO(303413)
Descrição geral
Myeloperoxidase (MPO) is a heme-containing enzyme that catalyzes the hydrogen peroxidase-mediated oxidation of halide ions to hypochlorous acid. MPO is a lysosomal protein, highly expressed in neutrophils, that plays a role in the antimicrobial actions that occur as a result of neutrophil stimulation. The actions of MPO may also contribute to the initiation and pathogenesis of cardiovascular disease.
Aplicação
MPO Colorimetric Activity Assay Kit has been used to determine the activity of myeloperoxidase in samples.
Características e benefícios
Compatible with high-throughput handling systems.
Adequação
Suitable for the measurement of myeloperoxidase (MPO) in biological samples such as tissue, cells, serum and white blood cells
Princípio
In this assay, MPO catalyzes the formation of hypochlorous acid, which reacts with taurine to form taurine chloroamine. Taurine chloroamine reacts with the chromophore TNB, resulting in the formation of the colorless product DTNB. One unit of MPO activity is defined as the amount of enzyme that hydrolyzes the substrate and generates taurine chloramine to consume 1.0 μmole of TNB per minute at 25 °C.
Palavra indicadora
Danger
Frases de perigo
Declarações de precaução
Classificações de perigo
Eye Irrit. 2 - Resp. Sens. 1 - Skin Irrit. 2
Código de classe de armazenamento
10 - Combustible liquids
Ponto de fulgor (°F)
188.6 °F
Ponto de fulgor (°C)
87 °C
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