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Documentos Principais

M8631

Sigma-Aldrich

Melanin

Synthetic

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About This Item

Número CAS:
8049-97-6
Número CE:
232-473-6
Número MDL:
MFCD00131581
Código UNSPSC:
12352204
NACRES:
NA.83

Nível de qualidade

100

Formulário

powder

temperatura de armazenamento

−20°C

InChI

1S/C18H10N2O4/c1-5-13-9-7(3-19-13)12-10-8(11(9)17(23)15(5)21)4-20-14(10)6(2)16(22)18(12)24/h3-4,19-20H,1-2H3

chave InChI

XUMBMVFBXHLACL-UHFFFAOYSA-N

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Descrição geral

Melanin is a vital pigment present on the surface structures of vertebrates, which contribute to skin color. It has three forms such as, eumelanin, pheomelanin and neuromelanin. Melanin has cation chelating and redox properties. It is a potent absorbent of light. Melanin functions as a chemoprotective and photoprotective pigment. Mutations in this gene are associated with oculocutaneous albinism, vitiligo, piebaldism and Waardenburg syndrome.

Aplicação

Melanin has been used:
  • in spectrophotometry
  • to study its effect on reverse transcription polymerase chain reaction (RT-PCR) inhibition and effect of BSA (bovine serum albumin) in overcoming the inhibition
  • as an absorber for skin layer in near-infrared tissue spectra
  • Raman spectroscopy

Nota de preparo

Prepared by oxidation of tyrosine with hydrogen peroxide.

Código de classe de armazenamento

11 - Combustible Solids

Classe de risco de água (WGK)

WGK 1

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

Equipamento de proteção individual

Eyeshields, Gloves, type N95 (US)

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Certificados de análise (COA)

Lot/Batch Number
BCCF0394
BCCB2921
BCBV7256
BCBS0826V
BCBS0826

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Removal of analyte-irrelevant variations in near-infrared tissue spectra
Yang Y, et al.
Applied Spectroscopy, 60(9), 1070-1077 (2006)
Constant rate of steady-state self-antigen trafficking from skin to regional lymph nodes
Yoshino M, et al.
International Immunology, 18(11), 1541-1548 (2006)
Diorders of Pigmentation
Zaidi Z, et al.
Treatment of Skin Diseases, 159-170 (2019)
Miguel J Beltrán-García et al.
PloS one, 9(3), e91616-e91616 (2014-03-22)
In pathogenic fungi, melanin contributes to virulence, allowing tissue invasion and inactivation of the plant defence system, but has never been implicated as a factor for host cell death, or as a light-activated phytotoxin. Our research shows that melanin synthesized
Melanin
Riley PA
The International Journal of Biochemistry & Cell Biology, 29(11), 1235-1239 (1997)
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