M2295
Myelin Basic Protein from guinea pig brain
≥80% (SDS-PAGE), lyophilized powder, from guinea pig brain
Sinônimo(s):
MBP
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About This Item
Produtos recomendados
fonte biológica
guinea pig brain
Nível de qualidade
Ensaio
≥80% (SDS-PAGE)
forma
lyophilized powder
nº de adesão UniProt
aplicação(ões)
cell analysis
temperatura de armazenamento
−20°C
Informações sobre genes
guinea pig ... MBP(100731253)
Descrição geral
Myelin Basic Protein (MBP) expressed in guinea pig brain contains 167 amino acids and has a molecular weight of 18,256Da.
Myelin basic protein (MBP), an important constituent of the myelin sheath of CNS (central nervous system). It is an autoimmunogen. MBP is mapped to human chromosome 18q.
Aplicação
Myelin Basic Protein from guinea pig brain has been used as a component in emulsion to induce experimental autoimmune encephalitis (EAE).
Ações bioquímicas/fisiológicas
Mutation of the myelin basic protein gene induces dysmyelination; used to induce experimental allergic encephalomyelitis.
Myelin basic protein (MBP) plays a vital role in formation of myelin sheath and is associated with the various neurological disorders. MBP function as an antigenic target in autoimmune disease experimental allergic encephalomyelitis (EAE). MBP plays an essential role in cytoskeletal turnover and membrane extension. Additionally, it is also involved in Fyn-mediated signaling pathways, sequestration of phosphoinositides and regulation of calcium homoeostasis. MBP functions as an in vitro substrate for mitogen-activated protein kinase (MAP) kinase and aids in the purification and functional studies of enzyme.
Qualidade
May contain traces of urea-glycine buffer salts.
Princípio
Used as a kinase substrate.
produto relacionado
Nº do produto
Descrição
Preços
Código de classe de armazenamento
11 - Combustible Solids
Classe de risco de água (WGK)
WGK 3
Ponto de fulgor (°F)
Not applicable
Ponto de fulgor (°C)
Not applicable
Equipamento de proteção individual
Eyeshields, Gloves, type N95 (US)
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