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L2643

Sigma-Aldrich

α-Lactose monohydrate

suitable for cell culture, BioReagent

Sinônimo(s):

β-D-Gal-(1→4)-α-D-Glc, 4-O-β-D-Galactopyranosyl-α-D-glucose, Milk sugar

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About This Item

Fórmula empírica (Notação de Hill):
C12H22O11 · H2O
Número CAS:
5989-81-1
Peso molecular:
360.31
Número MDL:
MFCD00150747
Código UNSPSC:
12352201
ID de substância PubChem:
24896320
NACRES:
NA.75

fonte biológica

bovine milk

Nível de qualidade

200

linha de produto

BioReagent

Ensaio

≥99% total lactose basis (GC)

forma

powder

técnica(s)

cell culture | mammalian: suitable

Impurezas

≤0.05% Glucose
≤4% β-lactose

solubilidade

water: 100 mg/mL, clear, colorless

cadeia de caracteres SMILES

[H]O[H].OC[C@H]1O[C@@H](O[C@H]2[C@H](O)[C@@H](O)[C@@H](O)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@H]1O

InChI

1S/C12H22O11.H2O/c13-1-3-5(15)6(16)9(19)12(22-3)23-10-4(2-14)21-11(20)8(18)7(10)17;/h3-20H,1-2H2;1H2/t3-,4-,5+,6+,7-,8-,9-,10-,11+,12+;/m1./s1

chave InChI

WSVLPVUVIUVCRA-KPKNDVKVSA-N

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Aplicação

α-Lactose monohydrate has been used:
  • as a component of fraction B of diluent M1 for dilution of ram semen
  • as a component of Platz diluent variant (PDV) for dilution of bottlenose dolphin semen
  • in the preparation of HyQ PF-Chinese hamster ovary (CHO) disaccharide media for the adaptation of CHO cell lines
  • for the preparation of protein-free chemically defined cell culture medium (PFCDM) for the adaptation of human embryonic kidney 293 (HEK293) cells

Código de classe de armazenamento

11 - Combustible Solids

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

Equipamento de proteção individual

Eyeshields, Gloves, type N95 (US)

Certificados de análise (COA)

Busque Certificados de análise (COA) digitando o Número do Lote do produto. Os números de lote e remessa podem ser encontrados no rótulo de um produto após a palavra “Lot” ou “Batch”.

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A Thiel et al.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 125, 528-539 (2019-02-06)
3-NOP (3-nitrooxypropanol) reduces enteric methane formation in ruminants. A series of ADME studies in rats, lactating goats and beef cattle was performed. 3-NOP was entirely absorbed from the GIT of rats: approximately 75% of the administered 3-NOP was eliminated as
T R Robeck et al.
Biology of reproduction, 70(5), 1340-1348 (2004-01-09)
Research was conducted to develop an effective method for cryopreserving bottlenose dolphin (Tursiops truncatus) semen processed immediately after collection or after 24-h liquid storage. In each of two experiments, four ejaculates were collected from three males. In experiment 1, three
Ling Zhang et al.
Theranostics, 10(24), 11339-11358 (2020-10-13)
Background: TSTA3 gene encodes an enzyme responsible for synthesis of GDP-L-fucose as the only donor in fucosylation. This study was designed to explore clinical value, function and underlying mechanism of TSTA3 in the development of esophageal squamous cell carcinoma (ESCC).
Dawn Sow Zong Leong et al.
Scientific reports, 7, 45216-45216 (2017-03-31)
Mammalian cells are generally considered to be unable to utilize polysaccharides for cell growth because the phospholipid bilayer in the cell membrane has very low permeability to sugars. With the recent discovery of the only known animal disaccharide transporter, a
Johannes Gursch et al.
Journal of pharmaceutical sciences, 104(10), 3481-3489 (2015-07-07)
Over the last years, continuous manufacturing has created significant interest in the pharmaceutical industry. Continuous filtration at low flow rates and high solid loadings poses, however, a significant challenge. A commercially available, continuously operating, dynamic cross-flow filtration device (CFF) is
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