K3125
Kojic acid
≥98.5% (HPLC), powder, tyrosinase inhibitor
Sinônimo(s):
2-Hydroxymethyl-5-hydroxy-γ-pyrone, 5-Hydroxy-2-hydroxymethyl-4H-4-pyranone
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About This Item
Fórmula empírica (Notação de Hill):
C6H6O4
Número CAS:
Peso molecular:
142.11
Beilstein:
120895
Número CE:
Número MDL:
Código UNSPSC:
12352106
ID de substância PubChem:
NACRES:
NA.77
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Nome do produto
Kojic acid,
Ensaio
≥98.5% (HPLC)
Nível de qualidade
Formulário
powder
pf
152-155 °C (lit.)
cadeia de caracteres SMILES
OCC1=CC(=O)C(O)=CO1
InChI
1S/C6H6O4/c7-2-4-1-5(8)6(9)3-10-4/h1,3,7,9H,2H2
chave InChI
BEJNERDRQOWKJM-UHFFFAOYSA-N
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Aplicação
Kojic acid has been used:
- as an inhibitor of tyrosinase in guinea pigs pigmented hyperopic (PH)
- as a reference inhibitor standard for screening tyrosinase inhibition
- as a positive control for inhibition of tyrosinase in B16F10 melanoma cells
Ações bioquímicas/fisiológicas
Kojic acid is derived from some fungal species such as, Aspergillus, Acetobacter and Penicillium.. It halts melanin synthesis by inhibiting tyrosinase enzyme. It is used in the preparation of skin whitening cosmetics. However, kojic acid usage is minimal in cosmetics, as it induces skin irritation by its unstability and cytotoxic nature during long storage. It is an antioxidant and elicits radioprotective effects on chelating with manganese and zinc.
Tyrosinase inhibitor.
Código de classe de armazenamento
11 - Combustible Solids
Classe de risco de água (WGK)
WGK 1
Ponto de fulgor (°F)
Not applicable
Ponto de fulgor (°C)
Not applicable
Equipamento de proteção individual
Eyeshields, Gloves, type N95 (US)
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