I5521

Monoclonal Anti-Interferon-γ antibody produced in mouse

clone 25718, purified immunoglobulin, lyophilized powder

• Sinônimo(s): Anti-IFN-γ
• Número MDL: MFCD00162308
• Código UNSPSC: 51111800
• NACRES: NA.41

Propriedades

• fonte biológica: mouse
• Nível de qualidade: 100
• conjugado: unconjugated
• forma do anticorpo: purified immunoglobulin
• tipo de produto de anticorpo: primary antibodies
• clone: 25718, monoclonal
• Formulário: lyophilized powder
• reatividade de espécies: human
• técnica(s): immunocytochemistry: 8-25 μg/mL using immersion fixed human peripheral blood mononuclear cells stimulated with PMA and ionomycin; neutralization: suitable
• Impurezas: endotoxin, tested
• Isotipo: IgG2a
• nº de adesão UniProt: P01579
• temperatura de armazenamento: −20°C
• modificação pós-traducional do alvo: unmodified
• Informações sobre genes: human ... IFNG(3458)

Descrição

Imunogênio

recombinant human interferon-γ, expressed and purified from Escherichia coli.

Ações bioquímicas/fisiológicas

Interferons (IFNs) are cytokines that are secreted in response to viral or bacterial infections and tumorigenesis. IFN-γ binds to specific receptor complex consisting of IFNγR1 and IFNγR2. There are many pathways that are mediated by IFN-γ binding such as JAK/STAT1, AP-1, NF-κB, STAT3 and STAT5. IFN-γ is pleotropic and performs various functions related to immune response, inflammation, differentiation and activation of T cells, cell cycle and apoptosis.

forma física

Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline containing 5% trehalose.

Nota de preparo

Purified using protein A affinity chromatography.

Exoneração de responsabilidade

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informações de segurança

• Código de classe de armazenamento: 11 - Combustible Solids
• Classe de risco de água (WGK): WGK 2
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable
• Equipamento de proteção individual: Eyeshields, Gloves, type N95 (US)