I2142

KN-62

≥95%, powder

• Sinônimo(s): (S)-5-Isoquinolinesulfonic acid 4-[2-[(5-isoquinolinylsulfonyl)methylamino]-3-oxo-3-(4-phenyl-1-piperazinyl)propyl]phenyl ester, 1-[N,O-bis(5-Isoquinolinesulfonyl)-N-methyl-L-tyrosyl]-4-phenylpiperazine
• Fórmula empírica (Notação de Hill): C₃₈H₃₅N₅O₆S₂
• Número CAS: 127191-97-3
• Peso molecular: 721.84
• Número MDL: MFCD00083180
• Código UNSPSC: 12352200
• ID de substância PubChem: 24895961
• NACRES: NA.77

Propriedades

• fonte biológica: synthetic (organic)
• Ensaio: ≥95%
• forma: powder
• cor: yellow
• pf: 130 °C
• solubilidade: 45% (w/v) aq 2-hydroxypropyl-β-cyclodextrin: 0.93 mg/mL; methanol: 10 mg/mL; DMSO: 12 mg/mL; chloroform: 20 mg/mL
• temperatura de armazenamento: −20°C
• cadeia de caracteres SMILES: O=S(OC1=CC=C(C[C@@H](C(N2CCN(C3=CC=CC=C3)CC2)=O)N(C)S(C4=CC=CC5=C4C=CN=C5)(=O)=O)C=C1)(C6=CC=CC7=C6C=CN=C7)=O
• InChI: 1S/C38H35N5O6S2/c1-41(50(45,46)36-11-5-7-29-26-39-19-17-33(29)36)35(38(44)43-23-21-42(22-24-43)31-9-3-2-4-10-31)25-28-13-15-32(16-14-28)49-51(47,48)37-12-6-8-30-27-40-20-18-34(30)37/h2-20,26-27,35H,21-25H2,1H3/t35-/m0/s1
• chave InChI: RJVLFQBBRSMWHX-DHUJRADRSA-N
• Informações sobre genes: human ... P2RX7(5027)

Descrição

Ações bioquímicas/fisiológicas

Selectively inhibits rat brain Ca²⁺/calmodulin-dependent protein kinase II.

Características e benefícios

This compound is featured on the Ca/CaMKs and P2 Receptors: P2X Ion Channel Family pages of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Informações de segurança

• Código de classe de armazenamento: 11 - Combustible Solids
• Classe de risco de água (WGK): WGK 3
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable
• Equipamento de proteção individual: Eyeshields, Gloves, type N95 (US)