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Documentos

G7501

Sigma-Aldrich

L-Glutamic acid di-tert-butyl ester hydrochloride

≥98%

Sinônimo(s):

L-Glutamic acid 1,5-bis(1,1-dimethylethyl) ester hydrochloride (1:1)

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About This Item

Fórmula empírica (Notação de Hill):
C13H25NO4 · HCl
Número CAS:
32677-01-3
Peso molecular:
295.80
Beilstein:
3573738
Número MDL:
MFCD00058003
Código UNSPSC:
12352209
ID de substância PubChem:
24895307
NACRES:
NA.26

product name

L-Glutamic acid di-tert-butyl ester hydrochloride,

Ensaio

≥98%

forma

powder

cor

white

temperatura de armazenamento

−20°C

cadeia de caracteres SMILES

Cl[H].[H][C@](N)(CCC(=O)OC(C)(C)C)C(=O)OC(C)(C)C

InChI

1S/C13H25NO4.ClH/c1-12(2,3)17-10(15)8-7-9(14)11(16)18-13(4,5)6;/h9H,7-8,14H2,1-6H3;1H/t9-;/m0./s1

chave InChI

LFEYMWCCUAOUKZ-FVGYRXGTSA-N

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Ações bioquímicas/fisiológicas

Glutamic acid di-tert butyl ester (GTBE) possesses convulsant properties in mice and rats. It might have unique pharmacological features that set it apart from other convulsant medications.
L-Glutamic acid di-tert-butyl ester is C-terminal and R-chain blocked derivative of L-glutamate that may be useful in the synthesis of substance P antagonistic peptides.

Código de classe de armazenamento

11 - Combustible Solids

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

Equipamento de proteção individual

Eyeshields, Gloves, type N95 (US)

Certificados de análise (COA)

Busque Certificados de análise (COA) digitando o Número do Lote do produto. Os números de lote e remessa podem ser encontrados no rótulo de um produto após a palavra “Lot” ou “Batch”.

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L-Glutamic acid diethyl ester hydrochloride 97%

Sigma-Aldrich

309346

L-Glutamic acid diethyl ester hydrochloride

L-Glutamic acid 5-methyl ester 99%

Sigma-Aldrich

858269

L-Glutamic acid 5-methyl ester

N10-(Trifluoroacetyl)pteroic acid 95%

Sigma-Aldrich

861545

N10-(Trifluoroacetyl)pteroic acid

2,3,5,6-Tetrafluorophenol 97%

Sigma-Aldrich

196789

2,3,5,6-Tetrafluorophenol

M Antoniou et al.
International journal of peptide and protein research, 40(5), 395-400 (1992-11-01)
Analogues of [Orn6]-SP6-11 have been synthesized in which the methionyl residue is replaced by glutamine gamma-carboxamide substituted derivatives. These analogues where tested in three in vitro preparations representative of NK-1, NK-2 and NK-3 receptor types. Substitution of the SCH3 group
W J Freed et al.
Neurobehavioral toxicology and teratology, 7(3), 275-278 (1985-05-01)
Glutamic acid di-tert butyl ester (GTBE) was found to have a pronounced convulsant effect in mice and rats, producing recurrent clonic convulsions combined with postural and respiratory disturbances in a dosage of 0.5 mmol/kg (148 mg/kg). Tert-butyl ester derivatives of
A Manolopoulou et al.
International journal of peptide and protein research, 41(4), 411-414 (1993-04-01)
Analogues of [Orn6]-SP6-11 have been synthesized in which the Met11-NH2 residue is replaced by the alpha, gamma-dimethyl, alpha, gamma-dibenzyl and alpha, gamma-di-tert-butyl esters of glutamic acid. These analogues were tested in three in vitro preparations representative of NK-1, NK-2 and

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