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G0545

Sigma-Aldrich

Anti-GABAA Receptor (γ2 subunit) (extracellular) antibody produced in rabbit

affinity isolated antibody, lyophilized powder

Sinônimo(s):

Anti-γ-Aminobutyric Acid Type A Receptor (γ2 subunit)

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About This Item

Número MDL:
MFCD06798448
Código UNSPSC:
12352203
NACRES:
NA.41

fonte biológica

rabbit

Nível de qualidade

200

conjugado

unconjugated

forma do anticorpo

affinity isolated antibody

tipo de produto de anticorpo

primary antibodies

clone

polyclonal

forma

lyophilized powder

reatividade de espécies

bovine, mouse, rat, human

técnica(s)

western blot: 1:200 using rat brain membrane

nº de adesão UniProt

P18507

Condições de expedição

dry ice

temperatura de armazenamento

−20°C

modificação pós-traducional do alvo

unmodified

Informações sobre genes

human ... GABRG2(2566)
mouse ... Gabrg2(14406)
rat ... Gabrg2(29709)

Imunogênio

synthetic peptide corresponding to amino acids 39-53 of rat GABAA receptor (γ2 subunit). The sequence is identical in human, mouse, and bovine. In chick, it is 13/15 residues identical.

forma física

Lyophilized from phosphate buffered saline, pH 7.4, 1% BSA, and 0.05% sodium azide.

Exoneração de responsabilidade

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Código de classe de armazenamento

11 - Combustible Solids

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

Certificados de análise (COA)

Busque Certificados de análise (COA) digitando o Número do Lote do produto. Os números de lote e remessa podem ser encontrados no rótulo de um produto após a palavra “Lot” ou “Batch”.

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David F Owens et al.
Nature reviews. Neuroscience, 3(9), 715-727 (2002-09-05)
In the mature brain, GABA (gamma-aminobutyric acid) functions primarily as an inhibitory neurotransmitter. But it can also act as a trophic factor during nervous system development to influence events such as proliferation, migration, differentiation, synapse maturation and cell death. GABA
Esa R Korpi et al.
Progress in neurobiology, 67(2), 113-159 (2002-07-20)
Neurotransmitter receptor systems have been the focus of intensive pharmacological research for more than 20 years for basic and applied scientific reasons, but only recently has there been a better understanding of their key features. One of these systems includes
Carolina A Oliva et al.
International journal of molecular sciences, 24(2) (2023-01-22)
In Octodon degus, the aging process is not equivalent between sexes and worsens for females. To determine the beginning of detrimental features in females and the ways in which to improve them, we compared adult females (36 months old) and
Ann J Johnston et al.
Neurobiology of disease, 64, 131-141 (2014-01-11)
Genetic mutations in voltage-gated and ligand-gated ion channel genes have been identified in a small number of Mendelian families with genetic generalised epilepsies (GGEs). They are commonly associated with febrile seizures (FS), childhood absence epilepsy (CAE) and particularly with generalised

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