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Merck
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Key Documents

F4762

Sigma-Aldrich

Anti-Pig IgG (whole molecule)−FITC antibody produced in rabbit

IgG fraction of antiserum, buffered aqueous solution

Sinônimo(s):

Anti-Porcine IgG (whole molecule)−FITC antibody produced in rabbit, Anti-Swine IgG (whole molecule)−FITC antibody produced in rabbit

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About This Item

Número MDL:
Código UNSPSC:
12352203
NACRES:
NA.46

fonte biológica

rabbit

conjugado

FITC conjugate

forma do anticorpo

IgG fraction of antiserum

tipo de produto de anticorpo

secondary antibodies

clone

polyclonal

forma

buffered aqueous solution

condição de armazenamento

protect from light

técnica(s)

direct immunofluorescence: 1:32

temperatura de armazenamento

−20°C

modificação pós-traducional do alvo

unmodified

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Descrição geral

Immunoglobulin G (IgG) belongs to immunoglobulin family and consists of gamma (γ) heavy chain in the constant (C) region. IgG is a widely expressed serum antibody. Monomeric structure of IgG constitutes two identical heavy chains and two identical light chains with a molecular weight of 50kDa and 25kDa respectively, the primary structure of this antibody also contains disulfide bonds involved in linking the two heavy chains, linking the heavy and light chains and resides inside the chains. IgG is further subdivided into four classes namely, IgG1, IgG2, IgG3, and IgG4 with different heavy chains, named γ1, γ2, γ3, and γ4, respectively. IgG is produced and released from CD5+B cells, the predominant lymphocytes in the neonatal cell repertoire.

Aplicação

Anti-Pig IgG (whole molecule)−FITC antibody produced in rabbit has been used in direct immunofluorescent labeling.

Ações bioquímicas/fisiológicas

Immunoglobulin G (IgG) participates in hypersensitivity type II and type III reactions. Maternal IgG is the only antibody transported across the placenta to the fetus. Maternal IgG passively immunizes the infants.

forma física

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide.

Exoneração de responsabilidade

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Código de classe de armazenamento

10 - Combustible liquids

Classe de risco de água (WGK)

nwg

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

Equipamento de proteção individual

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)


Certificados de análise (COA)

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Production of transgenic pigs over-expressing the antiviral gene Mx1
Yan Q, et al.
Cell regeneration (London, England), 3(1), 11-11 (2014)
Structure and function of natural antibodies
Casali P and Schettino EW
Current Topics in Microbiological Immunology, 37(1), 167-179 (1996)
Quanmei Yan et al.
Cell regeneration (London, England), 3(1), 11-11 (2014-11-20)
The myxovirus resistance gene (Mx1) has a broad spectrum of antiviral activities. It is therefore an interesting candidate gene to improve disease resistance in farm animals. In this study, we report the use of somatic cell nuclear transfer (SCNT) to
Jacqueline Fischer-Lougheed et al.
Immunology, 123(3), 390-397 (2007-10-06)
Synthetic anti-idiotypic antibodies represent a potentially valuable tool for the isolation and characterization of B cells that produce xenoantibodies. An anti-idiotypic antibody that binds to a subset of B cells producing antibodies encoded by the variable-region heavy chain 3 (V(H)3)
Human placental Fc receptors and the transmission of antibodies from mother to fetus.
Simister NE and Story CM
Journal of Reproductive Immunology, 37(1), 1-23 (1997)

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