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Documentos Principais

E6902

Sigma-Aldrich

Elastin, soluble from human aorta

lyophilized powder

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About This Item

Número CAS:
9007-58-3
Número CE:
232-701-4
Número MDL:
MFCD02687373
Código UNSPSC:
12352202

fonte biológica

human aorta

Nível de qualidade

100

forma

lyophilized powder

técnica(s)

cell culture | mammalian: suitable

Impurezas

salt, free

nº de adesão UniProt

P15502

temperatura de armazenamento

2-8°C

InChI

1S/C27H48N6O6/c1-9-17(6)23(32-24(36)19(13-15(2)3)30-18(7)34)26(38)29-14-21(35)31-22(16(4)5)27(39)33-12-10-11-20(33)25(37)28-8/h15-17,19-20,22-23H,9-14H2,1-8H3,(H,28,37)(H,29,38)(H,30,34)(H,31,35)(H,32,36)/t17-,19-,20-,22-,23-/m0/s1

chave InChI

DPUYCSDGMSDKKV-MKBYFEBXSA-N

Informações sobre genes

human ... ELN(2006)

Ações bioquímicas/fisiológicas

Elastin, along with fibrillin, is responsible for the elastic properties of skin and arteries. Reported inhibitor of Clostridial collagenase.

Nota de preparo

Prepared from E6777 using the method of Partrige, et al.

Código de classe de armazenamento

11 - Combustible Solids

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

Equipamento de proteção individual

Eyeshields, Gloves, type N95 (US)

Certificados de análise (COA)

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Colesterol Sigma Grade, ≥99%

Sigma-Aldrich

C8667

Colesterol

E H Sage et al.
Advances in experimental medicine and biology, 79, 291-312 (1977-01-01)
The aortae of a number of vertebrates and invertebrates were tested for the presence of elastin to determine when this protein first appears phylogenetically. Using several criteria, including amino acid composition, presence of desmosines, and histological characteristics, we found that
Jinzhi Li et al.
BMC cancer, 20(1), 217-217 (2020-03-17)
Colorectal cancer (CRC) is the most common cancer and a leading cause of death worldwide. Extracellular matrix (ECM) proteins regulate tumor growth and development in CRC. Elastin (ELN) is a component of ECM proteins involved in the tumor microenvironment. However
The chemistry of connective tissues. 2. Soluble proteins derived from partial hydrolysis of elastin.
S M PARTRIDGE et al.
The Biochemical journal, 61(1), 11-21 (1955-09-01)
Aleksandra Kuzan et al.
Folia histochemica et cytobiologica, 59(1), 8-21 (2021-02-10)
Extracellular matrix (ECM) proteins have been associated with atherosclerotic complications, such as plaque rupture, calcification and aneurysm. It is not clear what role different types of collagen play in the pathomechanism of atherosclerosis. The aim of the study was to
Tony Collins et al.
Microbial cell factories, 12, 21-21 (2013-03-01)
Silk-elastin-like proteins (SELPs) combining the physicochemical and biological properties of silk and elastin have a high potential for use in the pharmaceutical, regenerative medicine and materials fields. Their development for use is however restrained by their production levels. Here we
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